How do mechanics, neural drive and muscle architecture interact in muscles?

这个项目将通过使用实验和个性化的计算模型来确定当肌肉移动和变形时，个人的肌肉活动、肌肉结构和机械特性以及肌肉周围的局部机械条件是如何相互作用的，这些因素和它们的相互作用可以同时进行检验。为了实现这一目标，我们将开发新的磁共振成像方法来测量人类肌肉的机械性能，并建立肌肉模型的方法。除了回答有关肌肉功能的基本科学问题外，这些新技术还将为研究其他肌肉提供平台，并为未来肌肉训练方法和技术的发展提供优化肌肉功能的平台。

This project will determine how an individual person’s muscle activity, muscle structure and mechanical properties, and the local mechanical conditions around the muscle interact as muscles move and deform, by using experiments and personalised computational models that can examine these factors and their interactions concurrently. To achieve this, we will develop novel magnetic resonance imaging methods to measure the mechanical properties of muscles in humans and methods for modelling muscles. As well as answering fundamental scientific questions about muscle function, these new techniques will provide a platform for studying other muscles, and for future development of muscle training methods and technologies to optimise muscle function.