Measuring large deformation tissue mechanical behaviour in living humans

测量活人大变形组织机械行为

• 批准号: DP160100061
• 负责人: Prof Lynne Bilston
• 金额: $ 43.81万
• 依托单位: The University of New South Wales
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-01-01 至 2019-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP160100061
• 关键词: Measuring; large; deformation; tissue; mechanical

This project aims to develop new in vivo imaging methods to characterise the nonlinear mechanical behaviour of soft biological tissues, and use them to measure the properties of muscle, liver and adipose tissue in human subjects. Comprehensively characterising the mechanical properties of an individual person’s body tissues in vivo is a long-standing challenge in biomechanics and biomedical engineering. These new methods aim to overcome major imitations of current biomechanical imaging methods, and make new measurements of the nonlinear mechanical properties of muscle, liver and adipose tissues. These techniques may be useful for future diagnostic, biomechanics and mechanobiology applications.

该项目旨在开发新的活体成像方法来表征生物软组织的非线性力学行为，并使用它们来测量人体肌肉、肝脏和脂肪组织的特性。在生物力学和生物医学工程中，全面表征活体人体组织的力学特性是一个长期存在的挑战。这些新方法旨在克服目前生物力学成像方法的主要模仿，并对肌肉、肝脏和脂肪组织的非线性力学性质进行新的测量。这些技术可能对未来的诊断、生物力学和机械生物学应用有用。