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Assessing the feasibility of developing Ai2's novel anti-infective peptide technology for topical anti-fungal applications.

Assessing the feasibility of developing Ai2's novel anti-infective peptide technology for topical anti-fungal applications.
评估开发 Ai2 新型抗感染肽技术用于局部抗真菌应用的可行性。
批准号:
131277
负责人:
金额:
$19.11万
依托单位:
依托单位国家:
英国
项目类别:
Feasibility Studies
财政年份:
2013
资助国家:
英国
项目状态:
已结题
起止时间:
2013 至 --

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中文摘要
翻译
Ai2是一家总部位于英国的生物技术公司,专门从事新型抗感染肽技术,将强效抗菌功效与卓越的安全性相结合。Ai2目前正在研究该技术的抗真菌功效,以确定开发为抗真菌剂的可行性。局部真菌感染是一种常见且日益增加的健康问题,其导致患者不适和痛苦,并可能导致潜在的致命性全身感染。目前可用的治疗具有显著的缺点,包括治疗时间长和抗性产生,因此需要更有效的药剂。该项目旨在确定所选肽对相关生物体的功效及其与人体组织的安全性和相容性。这将导致Ai2产生一个数据组合,证明进一步开发我们的技术作为抗真菌剂的可行性。
英文摘要
Ai2 is a UK-based biotechnology company specialising in novel anti-infective peptide technology combining potent antibacterial efficacy with excellent safety. Ai2 is now researching the antifungal efficacy of the technology to determine the feasibility of development as an antifungal agent. Topical fungal infections are a common and increasing health concern that cause discomfort and distress to patients and can lead to potentially fatal systemic infections. The currently available treatments have significant drawbacks including lengthy treatment time and resistance generation, therefore a more effective agent is needed. This project aims to establish the efficacy of selected peptides against relevant organisms and their safety and compatibility with human tissue. This would result in Ai2 generating a data portfolio that demonstrates the feasibility of developing our technology as an antifungal agent further.
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