Developing a nonpharmacological pain intervention for community dwelling older adults with dementia

为社区居住的痴呆症老年人开发非药物疼痛干预措施

• 批准号: 10644490
• 负责人: Annalisa Na
• 金额: $ 17.87万
• 依托单位: DREXEL UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-04-15 至 2027-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10644490
• 关键词: Acceleration; Adult; Aging; Alzheimer' s Disease; Alzheimer' s disease related dementia; Analgesics; Arts; Behavior; Behavior Therapy; Biological; Boxing; Caregiver Burden; Caregivers; Characteristics; Chronic; Clinical; Clinical Management; Clinical Trials; Cognitive; Communities; Complex; Creativeness; Dancing; Data; Degenerative polyarthritis; Dementia; Department chair; Development; Discipline of Nursing; Doctor of Philosophy; Dose; Elderly; Environment; Environmental Risk Factor; Exclusion; Exercise; Focus Groups; Funding; Future; Goals; Health Occupations; Health Services Accessibility; Health care facility; Home; Hybrids; Individual; Intervention; Interview; Joints; Knee; Knee Osteoarthritis; Knowledge; Leadership; Learning; Long-Term Care; Maps; Massage; Measures; Medical; Medicine; Mentors; Methodology; Modeling; Muscle; Music; Neurologist; Neurology; Neurosciences; Numeric Rating Scale; Nurses; Outcome; Pain; Pain management; Participant; Patients; Perception; Persons; Physical Function; Physical Rehabilitation; Physical therapy; Premature Mortality; Primary Care Physician; Psychosocial Factor; Quality of life; Reporting; Research; Research Assistant; Research Methodology; Research Personnel; Scientist; Structure; Testing; Therapeutic; Training; Training Activity; Translations; Treatment Efficacy; Universities; Utah; Weight-Bearing state; acceptability and feasibility; biopsychosocial; career; career development; chronic musculoskeletal pain; chronic pain; chronic pain management; college; community intervention; comorbidity; dementia care; design; distinguished professor; efficacy study; efficacy testing; evidence base; exercise program; experience; falls; implementation science; improved; innovation; interest; intervention program; knee pain; lens; mid-career faculty; non-drug; novel; osteoarthritis pain; personalized approach; physical therapist; preservation; professor; programs; prototype; rehabilitation science; skills; standard care; statistics; theories; therapy development; trial design

Candidate: I am an Assistant Research Professor in the Department of Physical Therapy and Rehabilitation Sciences at Drexel University. My long-term career goal is to establish a funded research program as an independent clinician-scientist working to develop evidence-based, pragmatic nonpharmacological programs to manage chronic pain in community-dwelling older adults with Alzheimer’s disease and Alzheimer’s-related dementias (AD/ADRD). To accomplish this goal, I will develop new knowledge and skills in: intervention development; mixed methodologies for intervention development, testing, and refinement; clinical trials using pragmatic and hybrid testing designs; grantsmanship; and research leadership. I will complete the following training objectives: 1) Build expertise in biopsychosocial environmental factors associated with comorbid chronic pain and AD/ADRD; 2) Develop skills in using different qualitative and quantitative methodologies for mapping and developing behavioral interventions that will promote engagement and use of tailored exercise programs by community-dwelling older adults with AD/ADRD; and 3) Gain and apply strategies for developing nonpharmacological pain interventions that have the potential to accelerate the translation of evidence into standard care. Mentoring Team: Joke Bradt, PhD (co-primary), Laura Gitlin, PhD, (co-primary), Peter Gliebus, MD (co-mentor), and Julie Fritz, PT, PhD (co-mentor). Dr. Bradt is a music therapist, Professor and Program Director of the Creative Arts Therapies Program and an expert in chronic pain management and mixed methods research. Dr. Gitlin is Dean and Distinguished University Professor of the College of Nursing and Health Professions and an expert in implementation science and the development of behavioral interventions tailored to the needs of community-dwelling older adults with AD/ADRD and their caregivers. Dr. Gleibus is a neurologist, Associate Professor at Drexel University College of Medicine, Chair of the Department of Neurology, and Director of the Global Neuroscience Institute, with expertise in the interdisciplinary clinical management of AD/ADRD. Dr. Fritz is a physical therapist, Associate Dean for Research and Distinguished Professor at the University of Utah with expertise in developing and implementing exercise-based interventions to manage chronic pain. The mentoring team will guide career development activities, give input, and participate in the K23 research. Research Strategy: The goal of the K23 project is to develop a tailored exercise program prototype to manage knee osteoarthritis pain in community-dwelling older adults with AD/ADRD that is feasible and accepted by key stakeholders. Aim 1: Identify delivery characteristics and design a prototype for a tailored exercise program that is informed in design by the 3-Step Tailored Approach. Aim 2: Assess the feasibility of delivering the tailored exercise program. Aim 3: Evaluate stakeholders’ perceived barriers and facilitators of the tailored exercise program. The proposed study uses an exploratory sequential design and aligns with NIA intervention development Stage I. The study will yield a prototype for a tailored exercise-based intervention program that has been refined for feasibility and acceptability among stakeholders.

我是德雷塞尔大学物理治疗和康复科学系的助理研究教授。我的长期职业目标是建立一个资助的研究项目，作为一名独立的临床科学家，致力于开发基于证据的、实用的非药物项目，以管理社区居住的老年阿尔茨海默病和阿尔茨海默病相关痴呆（AD/ADRD）的慢性疼痛。为了实现这一目标，我将在以下方面发展新的知识和技能：干预发展；干预开发、测试和改进的混合方法；采用实用和混合试验设计的临床试验；grantsmanship;以及研究领导力。我将完成以下培训目标：1)建立与共病慢性疼痛和AD/ADRD相关的生物心理社会环境因素的专业知识；2)培养使用不同定性和定量方法来绘制和制定行为干预措施的技能，这些干预措施将促进社区居住的老年AD/ADRD患者参与和使用量身定制的锻炼计划；3)获得并应用开发非药物疼痛干预措施的策略，这些策略有可能加速将证据转化为标准治疗。