Developing a nonpharmacological pain intervention for community dwelling older adults with dementia

为社区居住的痴呆症老年人开发非药物疼痛干预措施

基本信息

批准号：
10644490
负责人：
Annalisa Na
金额：
$ 17.87万
依托单位：
DREXEL UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-04-15 至 2027-03-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10644490
关键词：
Acceleration Adult Aging Alzheimer&apos s Disease Alzheimer&apos s disease related dementia Analgesics Arts Behavior Behavior Therapy Biological Boxing Caregiver Burden Caregivers Characteristics Chronic Clinical Clinical Management Clinical Trials Cognitive Communities Complex Creativeness Dancing Data Degenerative polyarthritis Dementia Department chair Development Discipline of Nursing Doctor of Philosophy Dose Elderly Environment Environmental Risk Factor Exclusion Exercise Focus Groups Funding Future Goals Health Occupations Health Services Accessibility Health care facility Home Hybrids Individual Intervention Interview Joints Knee Knee Osteoarthritis Knowledge Leadership Learning Long-Term Care Maps Massage Measures Medical Medicine Mentors Methodology Modeling Muscle Music Neurologist Neurology Neurosciences Numeric Rating Scale Nurses Outcome Pain Pain management Participant Patients Perception Persons Physical Function Physical Rehabilitation Physical therapy Premature Mortality Primary Care Physician Psychosocial Factor Quality of life Reporting Research Research Assistant Research Methodology Research Personnel Scientist Structure Testing Therapeutic Training Training Activity Translations Treatment Efficacy Universities Utah Weight-Bearing state acceptability and feasibility biopsychosocial career career development chronic musculoskeletal pain chronic pain chronic pain management college community intervention comorbidity dementia care design distinguished professor efficacy study efficacy testing evidence base exercise program experience falls implementation science improved innovation interest intervention program knee pain lens mid-career faculty non-drug novel osteoarthritis pain personalized approach physical therapist preservation professor programs prototype rehabilitation science skills standard care statistics theories therapy development trial design

项目摘要

Candidate: I am an Assistant Research Professor in the Department of Physical Therapy and Rehabilitation Sciences at Drexel University. My long-term career goal is to establish a funded research program as an independent clinician-scientist working to develop evidence-based, pragmatic nonpharmacological programs to manage chronic pain in community-dwelling older adults with Alzheimer’s disease and Alzheimer’s-related dementias (AD/ADRD). To accomplish this goal, I will develop new knowledge and skills in: intervention development; mixed methodologies for intervention development, testing, and refinement; clinical trials using pragmatic and hybrid testing designs; grantsmanship; and research leadership. I will complete the following training objectives: 1) Build expertise in biopsychosocial environmental factors associated with comorbid chronic pain and AD/ADRD; 2) Develop skills in using different qualitative and quantitative methodologies for mapping and developing behavioral interventions that will promote engagement and use of tailored exercise programs by community-dwelling older adults with AD/ADRD; and 3) Gain and apply strategies for developing nonpharmacological pain interventions that have the potential to accelerate the translation of evidence into standard care. Mentoring Team: Joke Bradt, PhD (co-primary), Laura Gitlin, PhD, (co-primary), Peter Gliebus, MD (co-mentor), and Julie Fritz, PT, PhD (co-mentor). Dr. Bradt is a music therapist, Professor and Program Director of the Creative Arts Therapies Program and an expert in chronic pain management and mixed methods research. Dr. Gitlin is Dean and Distinguished University Professor of the College of Nursing and Health Professions and an expert in implementation science and the development of behavioral interventions tailored to the needs of community-dwelling older adults with AD/ADRD and their caregivers. Dr. Gleibus is a neurologist, Associate Professor at Drexel University College of Medicine, Chair of the Department of Neurology, and Director of the Global Neuroscience Institute, with expertise in the interdisciplinary clinical management of AD/ADRD. Dr. Fritz is a physical therapist, Associate Dean for Research and Distinguished Professor at the University of Utah with expertise in developing and implementing exercise-based interventions to manage chronic pain. The mentoring team will guide career development activities, give input, and participate in the K23 research. Research Strategy: The goal of the K23 project is to develop a tailored exercise program prototype to manage knee osteoarthritis pain in community-dwelling older adults with AD/ADRD that is feasible and accepted by key stakeholders. Aim 1: Identify delivery characteristics and design a prototype for a tailored exercise program that is informed in design by the 3-Step Tailored Approach. Aim 2: Assess the feasibility of delivering the tailored exercise program. Aim 3: Evaluate stakeholders’ perceived barriers and facilitators of the tailored exercise program. The proposed study uses an exploratory sequential design and aligns with NIA intervention development Stage I. The study will yield a prototype for a tailored exercise-based intervention program that has been refined for feasibility and acceptability among stakeholders.

候选人：我是德雷克塞尔大学物理治疗与康复科学系的助理研究教授。我的长期职业目标是建立一项资助的研究计划，成为一项独立的临床科学家，致力于开发循证，实用的非药理学计划，以管理患有阿尔茨海默氏病和阿尔茨海默氏症相关痴呆症（AD/ADRD）的社区居民老年人的慢性疼痛。为了实现这一目标，我将发展新的知识和技能：干预开发；干预开发，测试和改进的混合方法；使用务实和混合测试设计的临床试验；授予技巧；和研究领导。我将完成以下培训目标：1）建立与合并症慢性疼痛和AD/ADRD相关的生物心理社会环境因素的专家； 2）开发技能，使用不同的定性和定量方法来绘制和开发行为干预措施，以促进和使用广告/ADRD的社区居住的老年人对量身定制的锻炼计划的使用； 3）获得并应用策略来开发非药物疼痛干预措施，这些干预措施有可能加速证据转化为标准护理。指导团队：Joke Bradt，PhD（联合著名），Laura Gitlin，PhD，（联合著作），彼得·格里布斯（Peter Gliebus），医学博士（Co-Incortor）和朱莉·弗里茨（Julie Fritz），PT，PT，PhD（Co-Encortor）。 Bradt博士是创意艺术疗法计划的音乐治疗师，教授兼计划主任，也是慢性疼痛管理和混合方法研究的专家。 Gitlin博士是护理与卫生专业人员学院的院长和杰出的大学教授，也是实施科学专家，以及针对有AD/ADRD及其护理人员的社区居民老年人的需求而量身定制的行为干预措施。 Gleibus博士是Drexel大学医学院的神经科医生，副教授，神经病学系主任和全球神经科学研究所主任，在AD/ADRD的跨学科临床管理方面具有专业知识。弗里茨博士是一名物理治疗师，研究副院长，犹他大学的杰出教授在开发和实施基于运动的干预措施方面具有专业知识来管理慢性疼痛。心理团队将指导职业发展活动，提供意见并参与K23研究。研究策略：K23项目的目的是开发一个量身定制的运动计划原型，以管理具有广告/ADRD社区居民的膝盖骨关节炎疼痛，这是主要利益相关者可行和接受的。 AIM 1：确定交付特征并为量身定制的运动计划设计原型，该计划通过三步量身定制的方法在设计中告知。目标2：评估提供量身定制的运动计划的可行性。目标3：评估利益相关者的感知障碍和量身定制运动计划的促进者。拟议的研究采用了探索性的顺序设计，并与NIA干预开发阶段I保持一致。该研究将为量身定制的基于运动的干预计划提供原型，该计划已完善，以使利益相关者之间的可行性和可接受性。