Caveospheres: A versatile peptide delivery system

纳米技术有可能改变我们治疗许多疾病的方式。该项目将研究一种新型纳米颗粒--空泡球，并测试其作为多肽递送系统的有效性。空泡球可以保护精致的货物不被降解，将货物靶向特定的细胞，诱导最大的治疗反应，并可以在大规模、经济高效的分批发酵中合成。这项研究将： 1：将生物功能改造成洞穴 2：研究工程洞穴的细胞行为 3：测定洞穴胶囊的体外治疗活性 它将对纳米颗粒在细胞中的运输有一个基本的了解，以改进纳米颗粒输送系统。

Nanotechnology has the potential to transform the way we treat many diseases. This project will investigate a new type of nanoparticle, the caveosphere, and tests its effectiveness as a peptide delivery system. Caveospheres can protect delicate cargo from degradation, target cargo to specific cells that induce the maximum therapeutic response, and can be synthesised in large-scale, cost-effective batch fermentation. This study will: 1: Engineer biological function into caveospheres 2: Investigate the cellular behavior of the engineered caveospheres 3: Determine the therapeutic activity of caveospheres in vitro It will develop a fundamental understanding of nanoparticles trafficking in cells, to make improved nanoparticle delivery systems.