Inflammation as an early form of maternal-fetal signalling in pregnancy

该项目旨在了解炎症信号在有袋动物妊娠中的作用。该项目有望解释为什么炎症，一个通常局限于损伤和感染的过程，是活产哺乳动物繁殖的一部分。该项目的成果包括强大的措施的能力，影响和演变，炎症信号在有袋动物怀孕。该项目将提供有关澳大利亚有袋动物群独特生物学的新知识，并将带来重大益处，包括增强澳大利亚的生殖研究能力，墨尔本和耶鲁大学之间的新国际合作，以及对炎症在妊娠中令人困惑的作用的新解释。

The project aims to understand the role of inflammatory signalling in marsupial pregnancy. This project is expected to explain why inflammation, a processes normally confined to injury and infection, is a part of reproduction in live-bearing mammals. Outcomes of this project include robust measures of the capacity for, impact of, and evolution of, inflammatory signalling in marsupial pregnancy. The project will provide new knowledge about the unique biology of Australia's marsupial fauna.This project will provide significant benefits, including enhanced capacity for reproduction research in Australia, new international collaborations between Melbourne and Yale, and a new explanation for the puzzling role of inflammation in pregnancy.