MOLECULAR GENETICS OF PHOTOTRANSDUCTION
MOLECULAR GENETICS OF PHOTOTRANSDUCTION
批准号:
2163464
负责人:
BIH-HWA SHIEH
金额:
$20.62万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
1993
资助国家:
美国
项目状态:
已结题
起止时间:
1993-04-01 至 1997-03-31
关键词:
Drosophilidae electrophysiology electroretinography gene deletion mutation gene expression gene mutation genetic markers immunoprecipitation membrane proteins nucleic acid sequence polymerase chain reaction posttranslational modifications visual photoreceptor visual phototransduction visual pigments voltage /patch clamp
中文摘要
长远目标是为低视力患者提供负担得起的医疗服务
最大限度地利用剩余视力进行阅读--在家里、工作场所、学校
和大多数其他地点。 阅读助理和阅读服务将
定制和整合计算机和通信技术,
关于如何最好地向患者显示文本的临床研究结果
特定类别的视力损害,包括与年龄有关的损失。
第一阶段的目标是:
1)开发和测试专用字体,以提高患者的识别能力
2)确定在监护仪上向患者显示文本的最佳方法
3)测量阅读速度和理解力,使用和不使用
显示器、字体和演示样式
4)评估改进扫描和OCR的要求
方法:测量四个学科类别的阅读功能,
包括老年人和年轻人,有和没有新的艾滋病。
技术创新将导致包装的小型化
组件整合到定制的集成系统中,以支持患者的双重
需要:改进剩余视力的使用和便携性。 没有设备,
具有所有这些属性的服务目前都存在。 目标价更多
比现有的部分解决方案更便宜。
英文摘要
The long-term objective is to offer low-vision patients affordable means
of maximizing use of residual vision for reading - at home, work, school
and most other locations. Reading Assistant and Reading Service will
customize and integrate computer and communication technologies with
results of clinical research on how best to display text to patients with
specific categories of visual impairment, including age-related losses.
Aims of Phase I are:
1) Develop and test specialized fonts for improved recognition by patients
2) Determine best method(s) of presenting text to patients on monitor
3) Measure reading speed and comprehension with and without use of
monitor, fonts and presentation styles
4) Assess requirements for improvements in scanning and OCR
Methodology: measure reading function of four subject categories,
including both old and young subjects, with and without new aids.
Technological innovation will result from packaging of miniaturized
components into integrated system customized to support patients' dual
needs: improved use of residual vision, and portability. No devices and
services with all these attributes currently exist. Target price is more
affordable than available partial solutions.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Regulation of Drosophila arrestins in light adaptation
-
批准号:8045425
-
项目类别:
-
资助金额:$37.01万
-
财政年份:2009
-
负责人:BIH-HWA SHIEH
-
依托单位:
Regulation of Drosophila arrestins in light adaptation
-
批准号:7635066
-
项目类别:
-
资助金额:$38.66万
-
财政年份:2009
-
负责人:BIH-HWA SHIEH
-
依托单位:
Regulation of Drosophila arrestins in light adaptation
-
批准号:8247060
-
项目类别:
-
资助金额:$37.07万
-
财政年份:2009
-
负责人:BIH-HWA SHIEH
-
依托单位:
Regulation of Drosophila arrestins in light adaptation
-
批准号:7797435
-
项目类别:
-
资助金额:$38.36万
-
财政年份:2009
-
负责人:BIH-HWA SHIEH
-
依托单位:
MOLECULAR GENETICS OF PHOTOTRANSDUCTION
-
批准号:2684555
-
项目类别:
-
资助金额:$25.97万
-
财政年份:1993
-
负责人:BIH-HWA SHIEH
-
依托单位:
Molecular Genetics of Phototransduction
-
批准号:6752811
-
项目类别:
-
资助金额:$33.98万
-
财政年份:1993
-
负责人:BIH-HWA SHIEH
-
依托单位:
Molecular Genetics of Phototransduction
-
批准号:6874842
-
项目类别:
-
资助金额:$33.98万
-
财政年份:1993
-
负责人:BIH-HWA SHIEH
-
依托单位:
MOLECULAR GENETICS OF PHOTOTRANSDUCTION
-
批准号:6180014
-
项目类别:
-
资助金额:$27.51万
-
财政年份:1993
-
负责人:BIH-HWA SHIEH
-
依托单位:
MOLECULAR GENETICS OF PHOTOTRANSDUCTION
-
批准号:2888411
-
项目类别:
-
资助金额:$26.71万
-
财政年份:1993
-
负责人:BIH-HWA SHIEH
-
依托单位:
Molecular Genetics of Phototransduction
-
批准号:6624209
-
项目类别:
-
资助金额:$33.98万
-
财政年份:1993
-
负责人:BIH-HWA SHIEH
-
依托单位:
MOLECULAR GENETICS OF PHOTOTRANSDUCTION
-
批准号:3267111
-
项目类别:
-
资助金额:$19.38万
-
财政年份:1993
-
负责人:BIH-HWA SHIEH
-
依托单位:
MOLECULAR GENETICS OF PHOTOTRANSDUCTION
-
批准号:2163465
-
项目类别:
-
资助金额:$20.59万
-
财政年份:1993
-
负责人:BIH-HWA SHIEH
-
依托单位:
Molecular Genetics of Phototransduction
-
批准号:7049436
-
项目类别:
-
资助金额:$33.18万
-
财政年份:1993
-
负责人:BIH-HWA SHIEH
-
依托单位:
MOLECULAR GENETICS OF PHOTOTRANSDUCTION
-
批准号:2019837
-
项目类别:
-
资助金额:$30.34万
-
财政年份:1993
-
负责人:BIH-HWA SHIEH
-
依托单位:
Molecular Genetics of Phototransduction
-
批准号:6473007
-
项目类别:
-
资助金额:$34.0万
-
财政年份:1993
-
负责人:BIH-HWA SHIEH
-
依托单位:
MOLECULAR GENETICS OF PHOTOTRANSDUCTION
-
批准号:2163466
-
项目类别:
-
资助金额:$21.2万
-
财政年份:1993
-
负责人:BIH-HWA SHIEH
-
依托单位:
海外基金