Molecular networks underlying mitochondrial biogenesis in humans

线粒体对生命至关重要，我们提出了一种高度创新的方法（采用多种尖端的“组学”技术和生物信息学），以促进对线粒体如何响应和适应人类运动的基本理解。 项目成果应包括重要的新知识和先进的专门知识，可供他人使用，以促进更多的研究成果。该项目预计创新工具将为分子生物学研究做出贡献，从而使治疗和生物技术应用受益。该项目将支持对年轻研究人员进行前沿技术的高级培训，这将扩大澳大利亚的研究能力，并有助于培养更高质量的劳动力。

Mitochondria are essential for life, and we propose a highly-innovative approach (employing multiple, cutting-edge ‘omic’ technologies and bioinformatics) to advance the fundamental understanding of how mitochondria respond and adapt to exercise in humans. The project outcomes should include significant new knowledge and advanced expertise that can be used by others to facilitate additional research outcomes. The project anticipates the contribution of innovative tools for molecular biology research, benefiting therapeutic and biotechnology applications. This project will support advanced training of young researchers in frontier technologies, which will expand Australian research capabilities and help produce a higher quality workforce.