Modular Vortex Fluidic Mediated Molecular Transformations

该项目旨在开发利用电场和磁场在易于扩展的连续流动条件下控制高剪切薄膜中的化学和生化反应，从而能够精确地构建复杂的功能分子。根据外部电场和磁场的方向、强度和频率，以及溶液中新的剪切应力诱导电场，可以提高反应速率，具有更高的收率和可调的选择性，并减少浪费和能源使用，这是使用传统的批量处理方法无法实现的。这将转化为分子装配线加工和新合成工具箱的开发，应用于制备药物。

The project aims to develop the use of electric and magnetic fields to control chemical and biochemical reactions in high shear thin films under readily scalable continuous flow conditions to then be able to precisely build complex functional molecules. Depending on the orientation, strength and frequency of external electric and magnetic fields, and novel shear stress induced electric fields in solution, rates of reactions can be enhanced, with higher yields and tunable selectivity, and reduced waste and energy usage, which is not possible using traditional batch processing. This will be translated into molecular assembly line processing and the development of a new synthetic toolbox, with applications in preparing pharmaceuticals.