ANTECEDENTS OF THE TYPE A BEHAVIOR PATTERN

描述：研究人员正在进行的研究的主要目的是 （a）确定儿童的早期出现和稳定性， 敌对行为及其相关的心理生理反应， 行为挑战，这是可能的风险因素， 成年期的心血管疾病;以及（B）详细说明其 决定因素和后果。在目前的赠款项目中， 以下横截面关系正在135个前和 青春期后儿童：（a）社会人口的影响 特征（美国黑人与白色美国人，男性与 女性，中产阶级和下层社会阶级）的发展， 儿童的倾向，包括敌对认知，低社会 家人和朋友的支持，以及血液动力学反应， 心理压力;（B）儿童倾向的影响 关键的生物风险因素，包括中心体脂肪， 静息压高胰岛素水平低高密度脂蛋白 胆固醇的影响;及（c）儿童的倾向及 左心室质量指数的生物学危险因素。 因为目前的项目长度从四个减少到三个 年，在下一个项目期间，目前的横截面研究将是 通过测试另外25名儿童完成。 然后， 将通过招募额外的 45名青春期前儿童，重新测试所有儿童（N=88）， 最初在青春期前，在青春期过渡的不同时间点， 重新测试所有最初是青春期后的儿童， 超声心动图评估（N=44）。这样，项目就可以进行测试 所提出的纵向关系可以在以下方面进行测试： 儿童的社会人口学特征和风险因素，描述 发展和青春期的影响，特别是对程度， 纵向关系，并进一步了解发展 从青春期到青年期的高风险轨迹。

DESCRIPTION: The major aims of the investigators' ongoing research have been: (a) to identify the early emergence and stability of children's hostile behaviors and their associated psychophysiological responses to behavioral challenges, which are possible risk factors for cardiovascular diseases in adulthood; and (b) to specify their determinants and consequences. During the current grant project, the following cross-sectional relationships are being tested in 135 pre- and post-pubertal children: (a) the influence of sociodemographic characteristics (being black American versus white American, male versus female, and middle versus lower social class) on the development of children's predispositions, including hostile cognitions, low social support from family and friends, and hemodynamic responses to psychological stress; (b) the influence of children's predispositions on key biological risk factors including central body fat, elevated resting pressure, high insulin levels, and low--high density lipid- cholesterol; and (c) the influence of children's predispositions and biological risk factors on left ventricular mass index. Because the current project was reduced in length from four to three years, in the next project period current cross-sectional study will be completed by testing an additional 25 children. Then the associations described above will be evaluated further by recruiting an additional 45 pre-pubertal children, retesting all children (N=88) who were initially prepubertal at various points in the pubertal transition, and retesting all children who were initially postpubertal and who completed echocardiographic assessments (N=44). In this way, the project can test the proposed longitudinal relationships can be tested among sociodemographic characteristics and risk factors in children, describe the effects of development and of puberty specifically on the extent of longitudinal relationships, and further understanding of the development of high risk trajectories from adolescence to young adulthood.