DESIGN OF A STEREOTAXIC RF BREAST BIOPSY COIL FOR MRI

磁共振成像（MRI）检测到乳腺病变， 以前是亚临床（既不可触及，也不能通过X线检测到 乳房X线照相术）。 然而，核磁共振成像40%的假阳性检出率 需要对这些亚临床病变进行活检以确诊。没有 存在允许在不打开的情况下执行此程序的设备 活检 因此，我们提出设计一个射频接收器 用于乳腺MR成像的线圈，具有集成的立体定位功能。 这 线圈将执行双重作用：从乳房接收信号以形成一个 磁共振成像，并允许磁共振成像引导活检和针定位。 该线圈将是3匝螺线管乳房线圈的改良版 TI 03，由PI设计，目前在临床上使用1.5特斯拉 GE Signa成像仪，位于俄亥俄州Willoughby Hills的MR成像中心。 线圈T103是 IRB批准，FDA批准预计今年晚些时候。十五 仅在美国就有100个中心表明了其商业应用 活检线圈的潜力。PI是一名博士。生物医学工程师， 6年以上0.3、0.6和1.5特斯拉MR成像仪经验，包括： 射频接收器线圈设计、成像协议和脉冲序列 改性

Magnetic resonance imaging (MRI) has detected breast lesions that had previously been sub-clinical (neither palpable nor detected by x-ray mammography). However, MRI's 40% false positive detection rate necessitates biopsy of these sub-clinical lesions to confirm diagnosis. No device exists that would allow this procedure to be performed without open biopsy. Therefore, we propose to design a radio frequency (rf) receiver coil for breast MR imaging with integrated stereotaxic capabilities. This coil would perform dual roles: receiving signal from the breast to form an MR image, and allowing MR imaging-guided biopsy and needle localizations. This coil will be a modification of the 3-turn solenoidal breast coil Tl03, designed by the PI, and currently in clinical use on the l.5-tesla GE Signa imager of MR Imaging center Willoughby Hills, Ohio. Coil T103 is IRB approved, and FDA approval is expected later this year. Fifteen hundred centers in the U.S. alone indicate commercial application potential for this biopsy coil. The PI is a Ph.D. biomedical engineer with over six years experience on 0.3, 0.6, and l.5-tesla MR imagers including: rf receiver coil design, imaging protocol, and pulse sequence modification.