The processing of fear in the medial temporal lobe

这个项目的目的是确定恐惧如何影响内侧颞叶(MTL)的信息处理。这对于首次系统评估恐惧如何改变MTL中不同类型信息的处理，包括无害信息；以及恐惧如何影响MTL网络中记忆的处理，包括它们的整合，具有重要意义。预期结果是关于这些恐惧影响的基本知识，以及解释它们的MTL功能理论。这一知识的好处是更好地了解信息在正常大脑中是如何处理的，从而更好地了解与恐惧相关的障碍对信息处理的干扰(例如，创伤后应激障碍中过度泛化的恐惧)。

The aim of this project is to identify how fear affects information processing in the medial temporal lobe (MTL). It is significant in providing the first systematic assessment of how fear alters processing of different types of information in the MTL, including the innocuous; and how fear affects processing of memories in MTL networks, including their integration. The expected outcomes are basic knowledge regarding these effects of fear, and a theory of MTL function in which they are explained. The benefit of this knowledge is a better understanding of how information is processed in a normal brain, and therefore, disturbances to information processing in fear-related disorders (e.g., over-generalization of fear in post-traumatic stress).