PREPARATION OF RADIOLABELED ANTI-AIDS COMPOUNDS

合成、采购、测试和分发放射性标记材料。 这种放射性标记的材料被壁内和壁外使用。 临床前和临床研究的校外研究者。 用于制备或采购放射性标记的 材料由项目官员制作，包括广泛的 各种化学物质和放射性原子， 重点在于所需标记材料的制备 通过使用碳14和氚的合成程序。 主要重点将放在准备所需的 放射性标记的化合物，并将涉及 各种各样的化合物 所需化合物可能包括 一种或多种放射性元素。 合成方法将是 在许多但不是所有情况下可用于“冷运行”。 开发新的和/或现有的合成程序应 必需的. 操作一个制备实验室，用于合成 放射性标记材料。 约5至10个放射性标记 每年的准备工作都要进行。 提供放射性标记材料的储存和分发， 大约50种化合物。 重量、包装和标签全部 发货，每月大约10至15次发货， 预期。

Synthesize, procure, test, and distribute radiolabeled materials. Such radiolabeled materials are used by intramural and extramural investigators for preclinical and clinical research. Assignments for preparation or procurement of radiolabeled materials are made by the Project Officer and include a wide variety of chemicals and radioactive atoms with the major emphasis being on the preparation of the desired labeled materials via synthetic procedures using carbon 14 and tritium. Major emphasis will be on the preparation of the desired radiolabeled compounds via synthetic procedures and will involve a wide variety of compounds. Compounds required may include one or more radioactive elements. Methods of synthesis will be available for "cold runs" in many, but not all, instances. Development of new and/or existing synthetic procedures shall be required. To operate a preparation laboratory for the synthesis of radiolabeled materials. Approximately 5 to 10 radiolabeled preparations per year should be anticipated. Provide storage and distribution of radiolabeled materials for approximately 50 compounds. Weight, package and label all shipments, approximately 10 to 15 shipments per month should be anticipated.