CONTINUATION OF FOLLOW-UP OF DES-EXPOSED COHORTS

该合同的目的是提供持续的后续行动， 充分表征的DES暴露队列的存活成员， 将用于估计整个人口的癌症风险， 大约有1000万人受到感染。 此外，现有 将合并并扩展队列，以包括先前未研究的 家庭中暴露的个体，因此总资源将增加价值 现有的较小的组件。 最后，可行性 将研究确定一组孙子女。 这项工作是 在环境流行病学分支（EEB）的支持下， 流行病学和生物统计学程序（EBP），癌症病因学部门 (DCE)国家癌症研究所（NCI）

The objective of this contract is to provide continued follow-up of surviving members of the well-characterized DES-exposed cohorts which will be used to estimate cancer risks in the entire population of approximately 10 million exposed individuals. In addition, existing cohorts will be combined and extended to include previously unstudied exposed individuals in the families, so the total resource will add value to the existing smaller components. Finally, the feasibility of identifying a cohort of grandchildren will be investigated. This work is being supported by the Environmental Epidemiology Branch (EEB), Epidemiology & Biostatistics Program (EBP), Division of Cancer Etiology (DCE) of the National Cancer Institute (NCI).