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DEPRESSION, PEPTIDES AND STEROIDS IN CUSHINGS SYNDROME

DEPRESSION, PEPTIDES AND STEROIDS IN CUSHINGS SYNDROME
库欣综合征中的抑郁症、肽和类固醇
批准号：
5216113
负责人：
MONICA N STARKMAN
金额：
$0.0万
依托单位：
--
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/5216113
关键词：
Cushing's syndrome adrenocorticotropic hormone clinical research cortisol depression endorphins hormone regulation /control mechanism human subject neuropharmacology prognosis psychopharmacology

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中文摘要
翻译
我们正在研究皮质醇、促肾上腺皮质激素和BLPH-B-内啡肽的分泌特征 基线条件下未接受治疗的库欣病患者 在CRH、甲吡酮和地塞米松激发期间。我们正在测试 抑郁症严重程度的异质性 (mood，认知和睡眠）与异质性有关， 皮质醇和垂体肽ACTH和BLPH-BE的分布。
英文摘要
We are studying cortisol, ACTH, and BLPH-B-endorphin secretory profiles in patients with untreated Cushing's Disease during baseline conditions and during CRH, metyrapone and dexamethasone challenge. We are testing the hypothesis that heterogeneity in the severity of depressive syndrome (mood, cognition, and sleep) is associated with heterogeneity in the profiles of cortisol and the pituitary peptides ACTH and BLPH-BE.
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会议论文
STEROIDS, COGNITION AND IMAGING IN CUSHING'S SYNDROME
VERB MEMORY & EMOTION PERCEPTION IN FMRI FOR CUSHING'S DISEASE PATIENTS
STEROIDS, COGNITION AND IMAGING IN CUSHING'S SYNDROME
VERB MEMORY & EMOTION PERCEPTION IN FMRI FOR CUSHING'S DISEASE PATIENTS
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