PHARMACOLOGICAL MANAGEMENT OF TEMPOROMANDIBULAR PAIN

描述：（申请人摘要） 颞下颌关节紊乱病是一组病症，其特征在于 颞下颌关节和/或咀嚼肌疼痛。 有这些症状的人通常会出现关节咔嗒声或爆裂声 并且因此可能具有有限的开口和降低的功能 容量 关于疼痛替代治疗有效性的数据 与TMD（TMP）相关的是缺乏，与TMD的人已经 接受了广泛的治疗-手术，非侵入性，行为， 和药理学。 本项目的目的是描述和分析 治疗颞下颌关节疼痛的药物 Kaiser Permanente Northwest Region Medical Care（KPNW） 和牙科保健（KPDCP）计划，使用电子信息 以及医疗和牙科治疗记录。 发病率估计数 治疗的TMP和TMP初始疗程的患病率 1967年至1991年期间KPNW成员将从纵向 25年的数据库 吸毒者的吸毒模式 TMP-包括类型，数量和分配的持续时间-将被描述 并利用电子信息进行分析， 医药数据库 药物制剂的成本 TMP的管理和相关后果-频率降低， 疼痛强度和残疾天数-将通过成本模型进行估计 通过病人问卷调查。

DESCRIPTION: (Applicant's Abstract) Temporomandibular joint disorders are a group of conditions characterized by pain in the temporomandibular joint and/or muscles of mastication. Individuals with these symptoms often present with joint clicking or popping and, consequently, may have limited opening and decreased functional capacity. Data on the effectiveness of alternative treatments for pain associated with TMD (TMP) is lacking, and persons with TMD have been subjected to a wide range of treatments-surgical, noninvasive, behavioral, and pharmacological. The purpose of this project is to describe and analyze the use of pharmaceutical agents in the management of temporomandibular pain (TMP) among members of the Kaiser Permanente Northwest Region medical care (KPNW) and dental care (KPDCP) programs using information available electronically and through medical and dental treatment records. Estimates of incidence and prevalence of treated TMP and of the initial course of therapy for TMP for KPNW members between 1967 and 1991 will be obtained from a longitudinal database spanning 25 years. Patterns of drug use for persons with TMP-including types, numbers, and duration of dispensings-will be described and analyzed using information available through an electronic pharmaceutical database. The costs of pharn1aceutical agents in the management of TMP and associated consequences-decreased frequency and intensity of pain and disability days-will be estimated through a cost model and through patient questionnaires.