DEVELOPMENTAL BIOLOGY AND GENETICS OF THE MAIZE LEAF

叶是重复枝段中最明显的部分 植物。单子叶植物的叶分成两部分：叶鞘 从植物中延伸出来的底座和刀片。我们的数据支持 叶实际上是基因结构域拼凑而成的概念。在 鞘-刀片边界为舌状区。在玉米方面，我们有很多 20个不同基因中的突变等位基因改变了全部或部分 刀鞘边界。其中五个是克隆的，还有几个是克隆的 其特点是我们可以对它们的功能发表一些看法。 一些编码同源结构域蛋白的类型已知是特别的 动物发育的重要转录调控因子。总体而言, 我们的目标是将这些基因的功能整合到一个系统中 场、域、感应、换能器和响应 “位置信息”和“发展时间表”的概念 可能会被区别开来。 也许我们工作最独特的方面是我们能够 遗传扰乱了各种发育的守时功能。我们可以的 获得异时转移的分子机制，这将是非常 在动物系统中很难做到。我们提出了一种抑制器屏幕来 获得专门加速发育或转化的突变体 植株的幼体部分要更成熟一些。我们已经开始减少 异时理论，与进化相关的流行概念 发展，到分子机制。

The leaf is the most visible part of the repeating shoot segment in plants. Monocotyledonous plants have leaves in two parts: the sheath at the base and the blade that extends out from the plant. Our data supports the concept that the leaf is actually a patchwork of gene domains. At the sheath-blade boundary is the ligular region. In maize, we have many mutant alleles in 20 different genes that alter all or a portion of the blade-sheath boundary. Five of these are cloned and several more are characterized to the level that we can say something about their function. Some encode homeodomain proteins of the type known to be particularly important transcriptional regulators of animal development. In general, our aim is to integrate the function of these genes into a system of fields, domains, inductions, transductions and responses where the related concepts of "positional information" and "developmental time schedules" might be distinguished. Perhaps the most unique aspect of our work is the way we are able to genetically perturb various developmental time-keeping functions. We can obtain molecular mechanisms for heterochronic shifts that would be very difficult to do in animal systems. We propose a suppressor screen to obtain mutants that specifically accelerate development or transform juvenile parts of the plant to be more adult. We have begun to reduce heterochronic theory, the prevailing concepts that relate evolution to development, to molecular mechanisms.