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Beyond Hendra: the significance of viral communities in bat virus spillover

Beyond Hendra: the significance of viral communities in bat virus spillover
超越亨德拉:病毒群落在蝙蝠病毒溢出中的重要性
批准号:
DE190100710
负责人:
Dr Alison Peel
金额:
$29.67万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Discovery Early Career Researcher Award
财政年份:
2019
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2019-06-20 至 2024-06-19

项目摘要

项目成果

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中文摘要
翻译
该项目旨在通过确定蝙蝠在同步脉冲中释放多种病毒的原因,来解决人畜共患蝙蝠传播病毒造成的全球健康威胁。该项目预计将确定多病毒脱落脉冲的通用驱动程序,使用亨德拉病毒作为澳大利亚和全球其他蝙蝠病毒的模型系统。预期成果包括深入了解环境变化,蝙蝠生态,病毒动力学和溢出之间的相互作用,预测何时何地蝙蝠病毒脱落最有可能发生,并制定新的生态干预措施,以防止蝙蝠病毒在澳大利亚和全球范围内溢出。这将通过在外溢和全球大流行病发生之前先发制人,带来重大利益。
英文摘要
This project aims to address the emerging global health threat posed by zoonotic bat-borne viruses, by determining why bats shed multiple viruses in synchronised pulses. The project expects to identify universal drivers of multi-viral shedding pulses, using Hendra virus as a model system for other bat viruses in Australia and globally. Expected outcomes include insights into the interactions between environmental change, bat ecology, viral dynamics and spillover, prediction of when and where bat viral shedding will most likely occur, and development of new ecological interventions to prevent bat virus spillover in Australia and globally. This will provide significant benefits by pre-empting spillover and global pandemics before they occur.
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