PEDIATRIC AIDS CLINICAL TRIALS UNIT

杜克儿科艾滋病临床试验中心是一个多中心项目 为感染和接触艾滋病毒的儿童提供ACTG方案护理 在北卡罗来纳州、弗吉尼亚州南部和南部北部 卡罗莱纳。以经济高效、地区性的方式提供这些服务 北卡罗来纳州儿童艾滋病网络(NC-CAN)是 已创建。网络的核心是杜克大学，那里的人数最多 的患者，数据输入和质量保证活动 以此为基础，并与几个大型基础科学计划发生接口。 北卡罗来纳大学教堂分校有一个完整的分部 Hill，从关注青少年开始(因为有很大的 血友病中心)，但已经进化到强调围产期预防 和初级治疗试验。北卡罗来纳州有两个外联诊所，位于 北卡罗来纳州夏洛特市的卡罗莱纳医疗中心和布伦纳儿童医院 北卡罗来纳州温斯顿-塞勒姆的鲍曼·格雷医学院的一家医院。至 为了服务这些诊所，杜克大学的一支医疗队前往 定期安排夏洛特和温斯顿-塞勒姆(每隔2至 每个站点4周)。在外展诊所，病人由 他们当地的儿科传染病专家提供护理，并由 杜克旅行团队为ACTG协议相关问题。因此，患者 可以在离当地社区更近的地方参加ACTG协议， 使患者更容易获得尖端医疗服务 这是一群普遍贫穷和处境不利的人群。旅游团队也 参与筛选北卡罗来纳州格林维尔(东卡罗来纳州)的诊所 大学医学院)和弗吉尼亚州罗阿诺克(社区医院 罗阿诺克山谷)，在那里患者被看到和评估 它们对ACTG议定书的适用性，同样是与其 当地的儿科传染病专家。除了……之外 NC-CAN模式提供离患者家更近的医疗护理 作为一个整体，允许Duke PACTU保持严格的质量保证， 由于表格是由杜克大学的工作人员填写的，并提供最佳 实验室标本交付，因为临床标本来自 外展和筛查诊所由ACTG认证的人员提供 北卡罗来纳大学和杜克大学的逆转录病毒学和细胞学实验室。

The Duke Pediatric AIDS Clinical Trials Unit is a multicenter program which provides ACTG protocol care to HIV infected and exposed children throughout North Carolina, southern Virginia, and northern South Carolina. To provide these services in a cost-effective, regional approach, the North Carolina Children's AIDS Network (NC-CAN) was created. The core of the network is at Duke, where the largest number of patients are seen, data entry and quality assurance activities are based, and interface occurs with several large basic science programs. There is a full sub-unit at the University of North Carolina at Chapel Hill, which began with a focus on adolescents (because of a large hemophilia center), but has evolved to emphasize perinatal prophylaxis and primary therapy trials. The NC-CAN has two Outreach Clinics, at the Carolinas Medical Center in Charlotte, NC, and the Brenner Children's Hospital at Bowman Gray School of Medicine in Winston-Salem, NC. To serve these clinics, a physician-nurse team from Duke travels to Charlotte and Winston-Salem on a regularly scheduled basis (every 2 to 4 weeks for each site). In the Outreach Clinics, patients are seen by their local pediatric infectious diseases specialist for care, and by the Duke Travel Team for ACTG protocol related issues. Thus, patients can participate in ACTG protocols closer to their local community, making access to cutting edge medical care more easily available for this generally poor and disadvantaged population. The Travel Team also participates in Screening Clinics in Greenville, NC (East Carolina University School of Medicine) and Roanoke, VA (Community Hospital of the Roanoke Valley) where patients are seen and evaluated regarding their suitability for ACTG protocols, again in coordination with their local pediatric infectious diseases specialists. In addition to providing medical care closer to the patients' homes, the NC-CAN model as a whole allows the Duke PACTU to maintain tight quality assurance, since the forms are completed by Duke staff, and to provide Optimum laboratory specimen delivery, since clinical specimens from the Outreach and Screening Clinics are hand delivered to ACTG certified retrovirology and cytometry labs at UNC and Duke (respectively).