Australian Heritage: constructing the first Aboriginal reference genome

该项目旨在利用DNA测序技术生成第一个完整和准确的原住民基因组，沿着澳大利亚各地的基因组变异图。它将联合收割机结合一系列先进的分析方法，将世界各地人类过去和现在的土著遗传多样性纳入一个新的泛人类参考基因组。该项目将导致我们对全球人类基因组变异的理解发生一步变化，并提供一系列与医学生物学相关的新靶点，同时显着提高我们对人类遗传历史及其现代后果的认识。

This project aims to use DNA sequencing technologies to generate the first complete and accurate Aboriginal genomes, along with maps of genomic variation around Australia. It will combine a range of advanced analytical methods to integrate past and present indigenous genetic diversity from human populations around the world into a new pan-human reference genome. This project will lead to a step change in our understanding of global human genomic variants and provide a range of new targets relevant to medical biology, while significantly improving our knowledge of human genetic history and its consequences in the modern day.