How an innocuous event never associated with danger becomes frightening

这个项目旨在利用动物模型研究恐惧记忆的组成部分是如何在内侧颞叶的特定区域巩固的。该项目旨在确定不同的组成部分是如何整合的，从而使以前从未与危险联系在一起的线索变得令人恐惧。这些知识有望提高对基本记忆过程和记忆缺陷的理解，这些记忆缺陷是与恐惧相关的障碍的特征。预期的好处包括改善创伤后应激障碍等疾病中的恐惧管理策略，以及发展关于动物如何产生对缺席事件的预期的新理论。

This project aims to investigate how the components of a fear memory are consolidated in specific regions of the medial temporal lobe using an animal model. The project intends to identify how the distinct components are integrated such that cues never before associated with danger become frightening. This knowledge is expected to improve understanding of basic memory processes and the failures of memory that characterise fear-related disorders. Intended benefits include improved strategies for the management of fear in disorders like post-traumatic stress, and development of new theories regarding the way in which animals generate expectations about absent events.