DEVELOPMENTAL RESEARCH PROGRAM IN PROSTATE CANCER

前列腺癌是美国男性最常见的癌症。 以及在乔治亚州，这是第二大原因 在美国和佐治亚州，男性癌症死亡的比例都很高。 前列腺癌的癌症统计数据的显著差异可能是 在白人男性和黑人男性之间。众所周知，黑人 美国人的前列腺癌发病率是世界上最高的，而前列腺癌 在美国，黑人的癌症发病率比白人高30%。 这项建议对RFA的回应是：1)开发一种互动的、 跨学科、协作的调查小组，共享 对前列腺癌研究的兴趣和专业知识，解决 研究问题的连续体，包括病因学、流行病学、风险 因素、病理、治疗、进展和预后因素；2)至 将发展方案的研究努力集中在一个统一的主题上 非裔美国人和高加索人之间的潜在差异 前列腺癌的诊断或被认为有风险；3)设计一种 计划正在进行的评估，以衡量其效果，以便 支持跨学科性质、确定的主题和增长，以及 研究项目的成长和成熟；4)支持创新 以及被评为有潜力的有价值的试点和可行性研究 成为同行评审、校外活动的最终成功接受者 资金问题。这些目标的实现，将由内部监督 节目策划委员会。制定新计划的计划内容 前列腺癌的研究将包括：识别关键 个人和项目支持的统一研究主题 探索性试点研究，其中四项初步资金建议为 包括在此应用程序中；创建内部机制 所有试点/可行性研究的征求意见、确定优先次序和提供资金； 组成一个外部咨询机构，其成员得到承认 前列腺癌研究领域的专家；招募新的、有资金的 调查人员将增加正在进行的项目开发和研究 努力；连续举办一系列研讨会，由杰出人士 演讲者与前列腺癌相关研究，以促进 跨学科互动和参与项目发展； 发起组织会议、务虚会和协商会议 宣传对发展至关重要的规划和评估过程 前列腺癌的一个跨学科的新研究项目。 机构资源和领导力致力于方案 目标，而埃默里大学处于一个独特的位置来调查 与病因和黑白相关的研究问题 前列腺癌的差异。

Prostate cancer is the most common form of cancer in males in the United States as well as in the state of Georgia, and is the second leading cause of cancer death in males, both in the United States and in Georgia. Significant differences in cancer statistics for prostate cancer can be seen between those for white males and black males. It is known that black Americans have the highest prostate cancer rates in the world, and prostate cancer incidence is 30% higher in blacks than whites in the U.S. The aims of this proposal in response to the RFA are: 1) To develop an interactive, interdisciplinary, collaborative group of investigators with shared interests and expertise in prostate cancer research, addressing the continuum of research questions including etiology, epidemiology, risk factors, pathology, therapy, progression, and prognostic elements; 2) To focus the research efforts of the developmental program on a unifying theme of potential differences between African-Americans and Caucasians with a diagnosis of or considered at-risk for prostate cancer; 3) To design a program plan an on-going evaluation to measure its effect in order to support the interdisciplinary nature, the identified theme, and growth and growth and maturation of the research program; 4) To support innovative and meritorious pilot and feasibility studies judged to have potential to become ultimately successful recipients of peer-reviewed, extramural funding. Accomplishment of these aims, will be overseen by an internal program Planning Committee. Elements of the plan to develop a new program in prostate cancer research will include: identification of key individuals and a unifying research theme for the program support for exploratory pilot studies, of which four proposals for initial funding are included with this application; creation of an internal mechanism for the solicitation, prioritization, and funding of all pilot/feasibility studies; formation of an external advisory broad of which the members are recognized experts in areas of prostate cancer research; recruitment of new, funded investigators to add to the ongoing program development and research efforts.; institution of a continuing seminar series with distinguished speakers related to prostate cancer research to facilitate interdisciplinary interaction and participation in program development; initiation of organizational meetings, retreats and consultation sessions to ad dress the planning and evaluation process critical to development of an interdisciplinary, new research program in prostate cancer. Institutional resources and leadership are committed to the programmatic goals, and Emory University is in a unique position to investigate the research questions related to etiological factors and black/white differences in prostate cancer.