EXTERNAL VALIDITY OF THE DSM IV SUBTYPES OF ADHD

描述（改编自申请人的摘要）： 拟议的研究是检查DSM-IV亚型的外部效度 注意力缺陷多动障碍，其中主要包括 注意力不集中（IA）、多动/冲动（HI）和组合（COM）亚型。 精神共病与执行功能的关系 (EF)将在各组之间比较任务。 有一些证据表明 不同群体之间的精神疾病，但更多的工作需要， 在这个领域做。 据预测，亚型将有 不同的精神相关性，与IA亚型相关性更高 高度与内化障碍和HI和COM组相关 外化障碍的发病率更高。 此外，很少有工作 对DSM-IV亚型的神经心理学特征进行了研究。 是 预测，神经心理学测试，轻拍抑制将是 差异受损的组，只有HI和COM亚型 显示与抑制能力直接相关的变量受损， 例如戈登的佣金错误和抑制百分比， 停止任务上的停止信号反应时间（SSRT）。 差异证据 精神病学特征和神经心理学特征将支持 DSM-IV亚型的外部效度。

DESCRIPTION (Adapted from Applicant's Abstract): The overall goal of the proposed research is to examine the external validity of the DSM-IV subtypes of Attention Deficit Hyperactivity Disorder, which include primarily inattentive (IA), hyperactive/impulsive (HI) and combined (COM) subtypes. Profiles of psychiatric comorbidity and performance on executive function (EF) tasks will be compared among the groups. There is some evidence of differential psychiatric disorders among the groups, but more work needs to be done in this area. It is predicted that the subtypes will have differential psychiatric correlates, with the IA subtype correlating more highly with internalizing disorders and the HI and COM groups correlating more highly with externalizing disorders. Further, very little work has been done on the neuropsychological profiles of the DSM-IV subtypes. It is predicted that the neuropsychological tests that tap inhibition will be differentially impaired in the groups, with only the HI and COM subtypes showing impairment on the variables directly relating to ability to inhibit, such as the commission errors on the Gordon and percent of inhibition and Stop Signal Reaction Time (SSRT) on the Stop Task. Evidence of differential psychiatric profiles and neuropsychological profiles would lend support for the external validity of the DSM-IV subtypes.