CORE--BIOSTATISTICS

生物统计共享资源(BSR)的主要目标是为亨斯迈癌症研究所(HCI‘s)癌症中心正在进行的基础、临床和流行病学研究提供生物统计学和生物数学支持。BSR为癌症中心社区提供广泛的服务，协助基础和临床研究人员进行研究设计、样本量/能量计算、数据分析以及准备演示文稿、拨款申请和手稿。重点是及早进行协商，以便充分考虑具体适应研究主要目标的研究设计。在过去的两年里，BSR的一项政策是更积极地寻求与癌症相关的生物统计学研究的最新发展所提出的合作，并应对具体应用中出现的方法学挑战。事实证明，这一政策卓有成效，大大增加了联合出版物的数量。预计未来几年对统计咨询服务的需求将大幅增加，因为癌症中心的快速发展和越来越多的用户明显受益于BSR的援助。此外，BSR将与微阵列资源合作的一个大型项目正在进行中，以便为新的微阵列图像技术的每个用户提供所需的定量分析。

The primary goal of the Biostatistics Shared Resource (BSR) is to provide biostatistical and biomathematical support for basic, clinical and epidemiological studies that are underway in the Huntsman Cancer Institute's (HCI's) Cancer Center. The BSR provides a wide spectrum of services to the Cancer Center community, assisting basic and clinical investigators with study design, sample size/power calculations, data analyses, and preparation of presentations grant applications and manuscripts. Emphasis is placed on early consultation to allow adequate consideration of study designs specifically adapted to the main objectives of the study. For the past two years, a policy of the BSR has been to more actively seek collaborations suggested by recent developments in cancer-related biostatistical research and to respond to methodological challenges emerging from specific applications. This policy has proven to be quite fruitful and has resulted in substantially increased number of joint publications. It is expected that the demands for statistical consulting services will increase substantially in the coming years because of a rapid development of the Cancer Center and an increasing number of users who have clearly benefitted from the BSR assistance. In addition, a large project is underway in which the BSR will collaborate with the Microarray Resource in order to provide every user of the new microarray image technology with the needed quantitative analysis.