EXTRAMURAL RESEARACH FACILITIES CONSTRUCTION PROJECTS

拟建的建筑为非人类灵长类动物(NHP)提供住所。 在符合适用政策的最先进设施中 标准。三个领域的计划增长需要额外的 为卫生保健计划提供住房。首先是克隆动物的生产。 ORPRC成功生产了核胚胎移植灵长类动物 满足了科学界前所未有的需求 获得这种资源，因为克隆动物灭绝了 遗传型变异。政府提供特别拨款，以加强和 加速该程序(RR12804、AI42709)的开发。最近的 新增Gerald Schatten博士指导辅助生殖 ORPRC的技术实验室将允许开发和利用 在这些独特的NHP中，最具临床相关性的模型是人类 疾病。第二个是搬迁R.S.陶氏神经科学研究所 由二零零零年一月一日起生效。这群人 大约20名科学家和他们的工作人员将占用新的实验室 空间，目前正处于设计阶段。该研究所将把 我们校园中的PI数量满足了对NHP住房的额外需求。 三是在传染病研究方面。在三年内， 传染病研究的PIS将增加一倍，从4个增加到8个。至 适应ABL 2和ABL 3大幅增加的要求 用于收容感染传染病的动物的隔离空间 研究表明，ORPRC将翻新老年动物空间，以满足这些需求， 减少了可用于传统住房的空间。新设施 提供现代化设施，为大约368个NHP提供住房。

The proposed construction provides housing for non-human primates (NHPs) in a state-of-the-art facility that complies with applicable policies and standards. Programmatic growth in three areas necessitates additional housing for NHPs. First is the production of clonally-derived animals. Successful production of nuclear embryo transplant primates at ORPRC has been met with an unprecedented demand from the scientific community for access to this resource, since clonally-derived animals eliminate genotypic variation. Special funding was provided to enhance and accelerate development of this program (RR12804, AI42709). The recent addition of Dr. Gerald Schatten to direct the Assisted Reproductive Technology Laboratory at ORPRC will allow the development and utilization of these unique NHPs as the most clinically relevant models for human disease. Second is the relocation of the R.S. Dow Neuroscience Institute to ORPRC (the OHSU West Campus) effective January 1, 2000. This group of approximately 20 scientists and their staff will occupy new laboratory space, presently in the design stage. This Institute will double the number of PIs on our campus pacing additional demands on NHP housing. Third is in infectious disease research. Within three years, the number of PIs in infectious disease research will double, from four to eight. To accommodate the requirement for a substantial increase in ABL 2 and ABL 3 containment space to house animals involved in infectious disease research, the ORPRC will renovate older animal space to meet these needs, reducing the space available for conventional housing. The new facility provides modern facilities housing for approximately 368 NHPs.