EXTRAMURAL RESEARACH FACILITIES CONSTRUCTION PROJECTS

拟议的建设为非人类灵长类动物（NHP）提供住房 在符合适用政策且 标准三个领域的方案增长需要增加 为NHP提供住房。首先是克隆衍生动物的生产。 在ORPRC成功生产核胚胎移植灵长类动物， 满足了科学界前所未有的需求， 获得这种资源，因为克隆衍生的动物消除 基因型变异提供了特别资金， 加速该项目的开发（RR12804，AI42709）。近期 Gerald Schatten博士加入指导辅助生殖 ORPRC的技术实验室将允许开发和利用 这些独特的NHP作为人类最临床相关的模型， 疾病第二是RS的迁移。陶氏神经科学研究所 ORPRC（OHSU西校区）于2000年1月1日生效。这群 大约20名科学家和他们的工作人员将占据新的实验室 空间，目前处于设计阶段。该研究所将使 我们校园内的PI数量增加了对NHP住房的额外需求。 第三是传染病研究。三年内， 传染病研究领域的PI将增加一倍，从4个增加到8个。到 满足ABL 2和ABL 3大幅增加的要求 用于饲养感染传染病动物的隔离空间 研究，ORPRC将翻新老年动物空间，以满足这些需求， 从而减小了可用于传统外壳的空间。新设施 为大约368名残疾人提供现代化设施住房。

The proposed construction provides housing for non-human primates (NHPs) in a state-of-the-art facility that complies with applicable policies and standards. Programmatic growth in three areas necessitates additional housing for NHPs. First is the production of clonally-derived animals. Successful production of nuclear embryo transplant primates at ORPRC has been met with an unprecedented demand from the scientific community for access to this resource, since clonally-derived animals eliminate genotypic variation. Special funding was provided to enhance and accelerate development of this program (RR12804, AI42709). The recent addition of Dr. Gerald Schatten to direct the Assisted Reproductive Technology Laboratory at ORPRC will allow the development and utilization of these unique NHPs as the most clinically relevant models for human disease. Second is the relocation of the R.S. Dow Neuroscience Institute to ORPRC (the OHSU West Campus) effective January 1, 2000. This group of approximately 20 scientists and their staff will occupy new laboratory space, presently in the design stage. This Institute will double the number of PIs on our campus pacing additional demands on NHP housing. Third is in infectious disease research. Within three years, the number of PIs in infectious disease research will double, from four to eight. To accommodate the requirement for a substantial increase in ABL 2 and ABL 3 containment space to house animals involved in infectious disease research, the ORPRC will renovate older animal space to meet these needs, reducing the space available for conventional housing. The new facility provides modern facilities housing for approximately 368 NHPs.