RESEARCH TRAINING IN ACADEMIC CARDIOLOGY

本申请请求继续支持埃默里大学医学院心内科的心血管研究博士后培训计划。拟议的计划将建立在已经成功的以实验室为基础的基础科学课程的基础上，该课程在培养杰出博士后研究员方面取得了令人印象深刻的记录。心脏病学研究部已被公认为氧化应激在血管疾病中的作用研究的领先者。这个项目的学员非常成功地在学术界获得了独立的职位。我们项目的13名毕业生是美国医学院的教员，7人在本国担任教职。我们已经有几位研究员获得或进入了国家青年调查员奖。在过去的5年里，360多篇来自接受该项目培训的研究员的手稿发表在同行评议的期刊上。要求为第一年的4名基础科学研究员和第二年的3名基础科学研究员提供两年的资金，在任何一年总共为7名基础科学研究员。此外，每年还要求为1名临床研究员提供一年的支持。这份申请中包含的17位导师提供了一个基础广泛的多学科环境，非常适合为学员提供出色的教育体验。参与的教职员工来自埃默里大学的心脏科、皮肤科、血液科/肿瘤科、生物化学、生物工程学和妇产科。它们都有既定的资金和出版记录，并在培训科学界有成效的成员方面取得了有据可查的成功。培训计划是围绕以导师为基础的环境构建的，并辅之以广泛的教育机会。总之，拟议的心血管研究培训计划将为基础和临床血管生物学的多学科培训提供一个独特的机会。成功的受训者将具备在学术心脏病学领域开始研究生涯的良好条件。

This application requests continued support for the postdoctoral training program in cardiovascular research in the Division of Cardiology at Emory University School of Medicine. The proposed program will build on an already successful laboratory-based basic science curriculum that has developed an impressive record of training outstanding postdoctoral fellows. The Cardiology Research Division has become recognized as a leader in research on the role of oxidative stress in vascular disease. The trainees of this program have been extremely successful in obtaining independent positions in academics. Thirteen graduates of our program are faculty members in American medical schools, and seven have taken faculty positions in their home countries. We have had several fellows who have been winners or finalists for national young investigator awards. In the past 5 years, over 360 manuscripts from fellows trained in this program were published in peer-reviewed journals. Two years of funding is requested for 4 basic science fellows in year 1 and 3 basic science fellows in year 2, for a total of 7 basic science fellows in any given year. In addition, one year of support is requested for 1 clinical research fellow every year. The 17 mentors included in this application provide a broad-based multi- disciplinary environment ideally suited to provide an outstanding educational experience for trainees. Participating faculty are drawn from the Divisions/Departments of Cardiology, Dermatology, Hematology/Oncology, Biochemistry, Bioengineering and Obstetrics/Gynecology at Emory University. All have an established funding and publication record as well as documented success in training productive members of the scientific community. The training program is structured around a mentor-based environment supplemented with an extensive array of didactic educational opportunities. In summary, the proposed cardiovascular research training program will provide a unique opportunity for multi-disciplinary training in basic and clinical vascular biology. Successful trainees will be well-equipped to initiate a research career in academic cardiology.