IMPAIRED AND PRESERVED MEMORY PROCESSES IN AMNESIA

描述（申请人的摘要）：该项目侧重于信息 遗忘症患者受损与完好作业的加工分析 在非文字记忆任务上，目标是指定记忆的性质， 依赖和不依赖于内侧颞叶和间脑的过程 大脑结构在健忘症中受损 本提案第一部分 详细探讨了健忘症中的内隐记忆现象， 特别是健忘症患者展示新形成的启动能力， 言语联想 为了说明哪些形式的联想 学习依赖于内侧颞区和间脑区， 研究人员将系统地研究健忘症患者在不同年龄段的表现。 一系列内隐记忆任务，其中新的联想启动发生在一个 知觉、词汇或概念层面。 第二部分 该提案关注健忘症患者在外显记忆任务中的表现， 检查是否以熟悉为基础的外显记忆受损， 基于回忆的外显记忆。 研究人员地址 这个问题通过直接测量记忆和熟悉度在一个 单个任务，无论是在基本过程和相关的水平， 意识 他们还将研究健忘症患者是否在 不同的外显记忆任务，被认为是不同的， 基础处理需求。 最后，他们将研究对 健忘症患者的几种操作的表现， 回忆 本提案的第三部分将审查 发生记忆错觉的健忘症，通过使用一个范例，在两个 外显记忆和内隐记忆，这一系列的研究提供了一个链接， 这两项研究都是在这个项目中进行的。

DESCRIPTION (Applicant's Abstract): This project focuses on an information processing analysis of the amnesic patient's impaired and intact performance on verbal memory tasks, with the goal of specifying the nature of the memory processes that do and do not depend on the medial temporal and diencephalic brain structures damaged in amnesia. The first section of this proposal explores in detail the phenomenon of implicit memory in amnesia and focuses specifically on amnesiacs' ability to demonstrate priming for newly formed verbal associations. In order to specify which forms of associative learning depend on the medial temporal and diencephalic regions, the researchers will systematically investigate amnesiacs' performance across a range of implicit memory tasks in which new associative priming occurs at a perceptual, lexical, or conceptual level. The second section of this proposal focuses on amnesiacs' performance on explicit memory tasks and examines whether familiarity-based explicit memory is impaired to the same extent as is recollection-based explicit memory. The researchers address this question by directly measuring recollection and familiarity within a single task, both in terms of underlying processes and associated levels of awareness. They will also examine whether amnesiacs are equally impaired on different explicit memory tasks that are thought to differ in their underlying processing demands. Finally, they will examine the effect on amnesiacs' performance of several manipulations that selectively influence recollection. The third section of this proposal will examine the occurrence of memory illusions in amnesia by using a paradigm in both explicit and implicit memory, this line of studies provides a link to the other two lines of studies in this proposal.