BIOCHEMICAL TOXICOLOGY MECHANISMS RESEARCH

本申请是培训补助金更新申请的第三次修订，每年支持4名博士前和2名博士后学生。 该计划的目标是培养环境毒理学家，他们将使用现代化学和生物化学研究技术来定义毒性损伤并探索毒物作用的机制。 该计划，而集中在药理学和毒理学博士。计划，还包括学生与强大的生物或化学训练谁可能会在他们的导师家庭部门内的其他程序注册。 建议康涅狄格大学的全职教师代表4所学院的8个部门和10名来自私营部门的毒理学家将担任项目教师。 学生将参加毒理学，药理学，病理学，分子生物学和统计学高级课程的核心课程，以及个性化的选修课。 毒理学专业的学生必须通过一系列全面的书面和口头考试，并公开捍卫他们的论文研究。 研究培训在计划的早期开始，并在第三年结束时接近全职。 对于博士后学员，可能需要有限的课程，这取决于背景。 所有受训人员将被要求参加研讨会、期刊俱乐部和毒理学学者座谈会，在国家或区域会议上介绍他们的研究，并在毒理学相关期刊上发表文章。

DESCRIPTION This application is the third revision of a renewal application for a training grant to support 4 predoctoral and 2 postdoctoral students per year. The objective of the program is to train environmental toxicologists who will use modern chemical and biochemical research techniques to define toxic injury and explore mechanisms of toxicant action. The program, while focused within the pharmacology and toxicology Ph.D. program, also includes students with strong biology or chemistry training who may be enrolled in other programs within the home departments of their mentors. It is proposed that full time University of Connecticut faculty representing 8 departments in 4 colleges and 10 toxicologists from the private sector will serve as program faculty. Students will take a core curriculum of advanced courses in toxicology, pharmacology, pathology, molecular biology and statistics, as well as individualized electives. Toxicology students must pass a series of comprehensive written and oral exams and publicly defend their dissertation research. Research training begins early in the program and progresses to near full time by the end of the 3rd year. For postdoctoral trainees, limited coursework may be required, depending upon background. All trainees will be required to participate in seminars, journal club and the toxicology scholars colloquium, to present their research at national or regional meetings, and to publish in toxicology-related journals.