PTSD IN CHILDREN WITH BURNS--A LONGITUDINAL STUDY

描述(改编自申请人的摘要)：宽泛的、长期的 该项目的目标是了解影响 创伤后症状的纵向病程 经历过类似创伤性事件的儿童，急性烧伤。 这项研究旨在确定各种生物、心理和社会因素的影响 创伤后症状出现和持续的变量 儿童因急性烧伤入院治疗。这样的知识可以促进 及早发现创伤后应激障碍的“高危”儿童。当前项目 建议对100名7岁至17岁的儿童进行评估 因急性烧伤住院的施林内斯·伯恩斯研究所 波士顿。儿童和家庭将在烧伤后不久进行评估，并 将收集有关创伤后应激障碍的各种“风险因素”的数据。 这些数据包括家庭压力，医疗干预的压力， 自尊和急性分离症状。儿童和家庭将成为 评估是否存在急性应激症状。唾液皮质醇和 将对MHPG和淋巴细胞糖皮质激素受体进行评估。 儿童在三个月、一岁和两岁后将被重新评估 出院了。在每一项评估中，儿童和 父母的创伤后症状，以及疼痛、身体等变量 形象、家庭压力、内科/外科治疗和神经内分泌 函数将被求值。数据将使用创新的 Willett(1988)提出的检验纵向数据的方法。这个 两年来每个儿童的创伤后症状的轨迹 这项研究将被策划。将使用多元回归分析来 确定所研究的变量影响过程的程度 这些症状。

DESCRIPTION (Adapted from applicant's abstract): The broad, long-term objectives of this proposed project are to understand variables influencing the longitudinal course of post-traumatic symptoms among a sample of children who have experienced a similar traumatic event, an acute burn. This study aims to determine the influence of a variety of biopsychosocial variables on the emergence and persistence of post-traumatic symptoms in children hospitalized with an acute burn. Such knowledge can facilitate the early identification of children "at risk" for PTSD. the current project proposes to evaluate 100 children between the ages of seven and seventeen who are hospitalized for an acute burn at the Shriners Burns Institute in Boston. Children and families will be evaluated shortly after the burn and data concerning a variety of "risk factors" for PTSD will be collected. Such data include family stress, the stress of medical intervention, self-esteem and acute dissociative symptoms. Children and families will be evaluated for the presence of acute stress symptoms. Salivary cortisol and MHPG, as well as lymphocyte glucocorticoid receptors, will be assessed. Children will be reassessed at three months, one year and two years after discharge from the hospital. At each of these assessments, child and parent's post-traumatic symptoms, as well as variables such as pain, body image, family stress, medical/surgical treatment, and neuroendocrine function will be evaluated. Data will be analyzed using an innovative approach to examining longitudinal data suggested by Willett (1988). The trajectories of each child's post-traumatic symptoms over the two years of the study will be plotted. Multiple regression analyses will be used to determine the degree to which the variables studied influence the course of these symptoms.