MACULAR CELL DEATH AND THE RETINAL PIGMENT EPITHELIUM

描述(摘自申请者摘要)：老年性黄斑 变性(ARMD)是65岁以上人群失明的主要原因 好几年了。该病导致光感受器细胞丢失和色素沉着 受影响区域的上皮细胞。这个项目的目的是为了获得一些 从内源性因素的影响看ARMD的发病机制 代谢物对眼部色素上皮存活的影响。

DESCRIPTION (Adapted from applicant's abstract): Age-related macular degeneration (ARMD) is the primary cause of blindness in people over age 65 years. The disease results in the loss of photoreceptor cells and pigmented epithelium in the affected area. This project is designed to gain some understanding of the origin of ARMD by examining the effect of endogenous metabolites on the survival of the pigment epithelium of the eye.