MATERNAL-FETAL HEMODYNAMICS RESPONSES TO EXERCISE

妇女越来越多地参加劳动力队伍和参加体育锻炼 已经授权对怀孕期间的运动进行重点研究。目前 科学文献在描述清楚和具体的方面是有限的。 促进产妇健康的运动指南，同时最大限度地减少胎儿 风险现有的孕妇运动指南是模棱两可的， 最好的，也许没有科学依据。 该计划的重点是检查产妇和胎儿 血液动力学影响的医学接受水平的急性，非 负重锻炼这个三年计划的主要目标是 是提高候选人在以下领域的知识和研究技能： 通过强化训练和广泛的指导， 本研究的主要目的是：（1）纵向评估 运动期间母胎血流动力学影响; 2）定义 运动强度与子宫动脉血流变化， 和脐动脉血流变化，同时监测胎儿安全; 3)评估整个妊娠期运动的安全限度，根据 对产妇心率、自觉心率等指标的影响。 本实验研究将采用重复测量设计， 健康、不吸烟、妊娠志愿者的样本（n=45）。母体心脏 心率、RPE、心输出量、每搏输出量、动脉压、子宫 动脉血流量和脐动脉血流量将在 不同的妊娠期和运动强度。运动测试 将采用不连续的、受时间限制的方案进行。的 这项研究最终将有助于制定明确的锻炼指南 为健康的孕妇，同时加强候选人的职业生涯， 这方面

The growing participation by women in the workforce and physical fitness has mandated a focused study of exercise during pregnancy. Currently, the scientific literature is limited in delineating clear and specific exercise guidelines for promoting maternal health while minimizing fetal risk. The existing exercise guidelines for pregnant women are equivocal at best and perhaps without scientific basis. The focus of the proposed program is to examine maternal and fetal hemodynamic repercussions of medically accepted levels of acute, non- weight-bearing exercise. The primary objective of this three-year program is to advance the candidate's knowledge and research skills in the area of exercise and pregnancy, by intensive training and extensive mentorship. The major aims of the proposed study are: 1) To assess longitudinally the maternal-fetal hemodynamic repercussions during exercise; 2) to define the relationships among exercise intensity, uterine artery blood flow change, and umbilical artery blood flow change, while monitoring fetal safety; and 3) to assess the safety limits of exercise throughout gestation, according to the indices of maternal heart rate and Rating of Perceived Exertion. This experimental study will employ a repeated-measures design with a sample of healthy, non-smoking, pregnant volunteers (n=45). Maternal heart rate, RPE, cardiac output, stroke volume, arterial pressure, uterine artery blood flow, and umbilical artery blood flow will be measured at different gestation periods and exercise intensities. The exercise tests will be conducted with a discontinuous, symptom-limited protocol. The study will ultimately aide development of unequivocal exercise guidelines for healthy pregnant women, while strengthening the candidate's career in this area.