Multiscale modelling and nondeterministic optimisation for reliable stents

该项目旨在研究建模和优化更可靠的血管内支架设计。血管内支架是一类终身支持血管恢复循环的微型装置。尽管其初步效果显著，但长期机械故障率高仍然是一个主要问题。该项目将研究不同长度尺度的塑性、疲劳损伤和断裂。所提出的优化有望最大限度地减少失败，从而提高支架治疗的寿命和可靠性。这将有显著的好处，例如适应支架和服务条件的变化，以实现持久可靠的治疗结果。

This project aims to study modelling and optimisation for a more reliable design of intravascular stents. Intravascular stents are a class of lifelong micro-devices to support blood vessel for restoring circulation. Despite its remarkable initial outcome, the high rate of long-term mechanical failure remains a major concern. This project will tackle plasticity, fatigue damage and fracture across different length scales. The proposed optimisation is expected to minimise failure, thereby enhancing the longevity and reliability of stent therapy. This will have significant benefits, such as accommodating variations in stents and service conditions for achieving a long-lasting and reliable therapeutical outcome.