PHYSICIAN SCIENTIST PROGRAM AWARD

医生-科学家奖计划的目标描述在 这一修改后的申请将同时满足我们对 处于领导地位的调查人员为我们快速发展 新的老龄化研究所成立于#年校园 1983年在加州大学圣地亚哥分校就读。这个 发现、培训和招募最聪明和最优秀的人 医学博士S走进临床相关课题研究领域 到老龄化也将满足国家研究所关于 衰老。医生在他们的早期临床培训将是 应邀申请为期五年的强化培训计划， 将使他们具备所需的强大的基础科学方向 对生物医学问题进行真正富有成效的研究。重点 在本提案中放在提供轨道上，以准备 考生对一些涉及到的问题进行研究 容易恶化的五个主要身体系统 随着年龄的增长，病理学的作用和发展。这个 头两到三年的培训将是最基本的 这样，受训者就可以，希望他们能解决前沿问题 使用前沿方法。在这一阶段的培训中， 候选人将被分配到在以下领域工作的教师赞助商 广泛适用于生物医学的基础学科 有问题。有直接的实验室研究经验 辅以说教培训，旨在填补他们在 基础科学背景，以及弥补在 曾接受过老年学和老年医学方面的教育。 因此，将自由使用丰富的基础科学菜单 在拉霍亚校园提供的课程，这将是 辅以组织严密的课程 老年病学/老年学。最后两三年的训练 将致力于研究与 感兴趣的五个集中区之一的病理生理学 致NIA。加州大学圣迭戈分校教职员工计划该项目的核心是 摘自生物系和化学系关于 综合校区，学院的基础和临床教师 医学和斯克里普斯诊所的研究基金会。他们 每一家都是根据其已证明的生产率来选择的 在研究方面和他们在培训计划中的记录。包括在内 是否有四名教职员工被选为美国国家科学院院士 科学。他们的目标将是发展这些 年轻的调查人员，这样五年后他们就会准备好 作为初级教员的全部责任与他们自己的 研究支持。

The aims of the Physician-Scientist Award Program described in this revised application will at the same time meet our needs for investigators in leadership positions for our rapidly-developing new Institute for Research on Aging established on the campus of the University of California San Diego in 1983. The identification, training and recruitment of the brightest and best M.D.'s into the arena of clinical investigation on subjects related to aging will also meet the objectives of the National Institute on Aging. Physicians in their early years of clinical training will be invited to apply for a five-year intensive training program that will equip them with the strong basic science orientation needed for truly productive research on biomedical problems. Emphasis in this proposal is placed on providing tracks that will prepare candidates to carry out research on problems relating to some five major body systems that are prone to deterioration in function and development of pathology with advancing years. The first two or three years of training will be at the most basic level so that the trainees can, it is hoped, attack frontier problems using frontier methods. During this phase of their training the candidates will be assigned to faculty sponsors working in fundamental disciplines of broad applicability to biomedical problems. Direct laboratory research experience will be supplemented by didactic training designed to fill gaps in their basic science background as well as to make up for gaps in previous education related to gerontology and geriatric medicine. Thus, liberal use will be made of the rich menu of basic science courses offered on the La Jolla campus and this will be supplemented by a well-organized course in geriatrics/gerontology. The last two or three years of training will be devoted to research problems bearing on the pathophysiology of one of the five concentration areas of interest to NIA. The nucleus of UCSD faculty planning for this program is drawn from the Departments of Biology and Chemistry on the general campus, the basic and clinical faculty of the School of Medicine, and the Research Foundation of Scripps Clinic. They have each been selected on the basis of their proven productivity in research and their track records in training programs. Included are four faculty honored by election to the National Academy of Sciences. They will have as their goal the development of these young investigators so that after five years they will be ready for full responsibility as junior faculty members with their own research support.