PHYSICIAN SCIENTIST PROGRAM AWARD

中所述的物理学家-科学家奖计划的目标 这一修改后的应用程序将同时满足我们的需求， 我们的快速发展的领导职位的调查员 新的老龄化研究所成立的校园， 1983年，加州圣地亚哥大学。 的 确定、培训和招聘最聪明和最优秀的 M.D.进入临床研究的竞技场， 也将满足国家研究所的目标， 衰老 医生在他们的早期临床培训将是 邀请申请一个为期五年的强化培训计划， 将为他们提供所需的强大的基础科学方向， 对生物医学问题进行真正富有成效的研究。 重点 在这个建议是放在提供轨道， 候选人进行研究的问题有关的一些 五个主要的身体系统，容易恶化， 病理学的作用和发展。 的 头两三年的培训将是最基本的 这样受训者就能解决前沿问题 使用前沿方法。 在这一阶段的训练中， 候选人将被分配到教师赞助商工作， 广泛适用于生物医学的基本学科 问题 直接实验室研究经验 辅以旨在填补其 基础科学背景，以及弥补差距， 曾接受过与老年医学和老年医学相关的教育。 因此，将自由使用基础科学的丰富菜单 在拉霍亚校园提供的课程，这将是 辅以精心组织的课程， 老年医学/老年学 过去两三年的训练 将致力于研究问题的影响， 关注的五个集中区域之一的病理生理学 到NIA。 加州大学圣地亚哥分校教师规划这个项目的核心是 从生物学和化学系中抽取， 一般校园，学校的基础和临床教师 医学和斯克里普斯诊所研究基金会。 他们 每一个都是根据他们的生产力被选中的 在研究和训练项目中的记录。 包括 有四名教师当选为国家科学院院士 以理工科为重 他们的目标是发展这些 年轻的研究人员，以便在五年后，他们将准备好 作为年轻的教师， 研究支持。

The aims of the Physician-Scientist Award Program described in this revised application will at the same time meet our needs for investigators in leadership positions for our rapidly-developing new Institute for Research on Aging established on the campus of the University of California San Diego in 1983. The identification, training and recruitment of the brightest and best M.D.'s into the arena of clinical investigation on subjects related to aging will also meet the objectives of the National Institute on Aging. Physicians in their early years of clinical training will be invited to apply for a five-year intensive training program that will equip them with the strong basic science orientation needed for truly productive research on biomedical problems. Emphasis in this proposal is placed on providing tracks that will prepare candidates to carry out research on problems relating to some five major body systems that are prone to deterioration in function and development of pathology with advancing years. The first two or three years of training will be at the most basic level so that the trainees can, it is hoped, attack frontier problems using frontier methods. During this phase of their training the candidates will be assigned to faculty sponsors working in fundamental disciplines of broad applicability to biomedical problems. Direct laboratory research experience will be supplemented by didactic training designed to fill gaps in their basic science background as well as to make up for gaps in previous education related to gerontology and geriatric medicine. Thus, liberal use will be made of the rich menu of basic science courses offered on the La Jolla campus and this will be supplemented by a well-organized course in geriatrics/gerontology. The last two or three years of training will be devoted to research problems bearing on the pathophysiology of one of the five concentration areas of interest to NIA. The nucleus of UCSD faculty planning for this program is drawn from the Departments of Biology and Chemistry on the general campus, the basic and clinical faculty of the School of Medicine, and the Research Foundation of Scripps Clinic. They have each been selected on the basis of their proven productivity in research and their track records in training programs. Included are four faculty honored by election to the National Academy of Sciences. They will have as their goal the development of these young investigators so that after five years they will be ready for full responsibility as junior faculty members with their own research support.