Cereals and rusts: molecular interactions for plant defence, food security

该项目旨在发现蛋白酶和蛋白酶抑制剂之间的基本分子相互作用，这些相互作用发生在谷物与其锈真菌病原体之间的持续冲突中。该研究结合了植物病理学、基因组学和功能蛋白质组学，并通过一种被称为基于活性的蛋白质谱的快速发展的实验方法得以实现。通过显著提高澳大利亚和海外谷物对锈病的抗性，这些知识和成果可能使植物育种者受益，从而加强全球粮食安全。

This project aims to discover the fundamental molecular interactions between proteases and protease inhibitors that occur in the ongoing conflict between cereals and their rust fungal pathogens. The research combines plant pathology, genomics and functional proteomics, and is enabled by a rapidly developing experimental approach known as activity-based protein profiling. The knowledge and outcomes potentially benefit plant breeders through significantly improved resistance of cereals to rust diseases in Australia and overseas, thereby enhancing global food security.