PERSEVERATION IN APHASIA

长期目标：本提案是一个计划的一部分， 临床和基础研究目标，长期目标是 阐明失语症患者的大脑行为关系。 有 新出现的证据表明，顽固是一个组成部分， 失语症综合征，可以是一个主要的威慑评估和 失语症患者的康复。 这里的重点是 失语症中的持续性沟通障碍以及 治疗持续和语言表现。 这项研究的目的是：1）测试两个最常被引用的 关于负责经常性疾病的潜在机制的假设 失语症的持续，即语义记忆痕迹的后激活 在短期记忆与运动记忆痕迹; 2）研究的影响， 失语症持续的特异性治疗; 3）研究患者的 意识到持续反应;和4）定性和 定量描绘患者持续性焦虑的演变过程 接受特定治疗的患者与未接受特定治疗的患者 接受持续性行为治疗。

Long Term Objective: This proposal is part o a program that combines clinical and basic research objectives, with the long term goal of elucidating brain-behavior relationships in aphasic patients. There is emerging evidence that perseveration is an integral component of some aphasia syndromes, and can be a major deterrent to evaluation and rehabilitation of aphasic individuals. The focus here is on the role of perseveration in the communication breakdown in aphasia and the effects of treatment on perseveration and language performance. The proposed research aims: 1) to test the two most commonly cited hypotheses regarding the underlying mechanisms responsible for recurrent perseveration in aphasia, i.e. post-activitation of semantic memory traces in short term memory versus motor memory traces; 2) to study the effects of specific treatment on aphasic perseveration; 3) to study patients' awareness of perseverative responses; and 4) to qualitatively and quantitatively chart the evolutionary course of perseveration in patients who receive specific treatment for perseveration versus those who do not receive treatment for perseveration.