JUVENILE DIABETES MELLITUS EPIDEMIOLOGY & ETIOLOGY
JUVENILE DIABETES MELLITUS EPIDEMIOLOGY & ETIOLOGY
批准号:
3227253
负责人:
ALLAN L DRASH
金额:
$60.59万
依托单位国家:
美国
项目类别:
财政年份:
1978
资助国家:
美国
项目状态:
已结题
起止时间:
1978-09-15 至 1993-11-30
关键词:
autoimmune disorder blood chemistry blood glucose blood group antigens case history diabetes mellitus genetics disease /disorder classification disease /disorder proneness /risk epidemiology family family genetics genetic markers genetic registry /resource /referral center genome human age group human genetic material tag human population genetics human subject immunogenetics immunoglobulins insulin dependent diabetes mellitus linkage mapping longitudinal human study metabolism disorder diagnosis patient /disease registry transposon /insertion element virus DNA virus related diabetes mellitus
中文摘要
这项拟议中的研究将评估免疫和
胰岛素依赖风险的环境决定因素
糖尿病(IDDM)。 具体而言,我们将:
1. 监测宾夕法尼亚州阿勒格尼县的胰岛素依赖型糖尿病发病率,
25年(1965-1990年),以及世界。
2. 评估特定血清学和
90例同胞中胰岛素依赖型糖尿病危险性的分子标记
58个受影响的父母子女家庭,60个单身家庭,
个案家庭
3. 评估病毒DNA插入到
人类基因组和胰岛素依赖型糖尿病。
4. 继续收集一级亲属的样本
转化为IDDM之前的病例。
英文摘要
The proposed research will evaluate the immunologic and
environmental determinants of the risk of insulin dependent
diabetes mellitus (IDDM). Specifically, we will:
1. Monitor the incidence of IDDM in Allegheny County, PA, over
25 years (1965-1990) as well as the world.
2. Assess the associations between specific serologic and
molecular markers to the risk of IDDM in 90 multiple sibling
families, 58 affected parent offspring families, and 60 single
case families.
3. Evaluate the association between viral DNA insertion into the
human genome and IDDM.
4. Continue to collect samples on first degree relatives of
cases prior to conversion to IDDM.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
ETIOLOGY AND EPIDEMIOLOGY OF INSULIN DEPENDENT DIABETES MELLITUS
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批准号:6246625
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项目类别:
-
资助金额:$1.91万
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财政年份:1996
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负责人:ALLAN L DRASH
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依托单位:
RESEARCH TRAINING IN PEDIATRIC ENDOCRINOLOGY & DIABETES
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批准号:2135404
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项目类别:
-
资助金额:$12.46万
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财政年份:1995
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负责人:ALLAN L DRASH
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依托单位:
DIABETES CONTROL AND COMPLICATIONS TRIAL
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批准号:3550669
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项目类别:
-
资助金额:$63.33万
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财政年份:1982
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负责人:ALLAN L DRASH
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依托单位:
DIABETES CONTROL AND COMPLICATIONS TRIAL
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批准号:3550668
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项目类别:
-
资助金额:$65.02万
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财政年份:1982
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负责人:ALLAN L DRASH
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依托单位:
DIABETES CONTROL AND COMPLICATIONS TRIAL (DCCT)
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批准号:3550663
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项目类别:
-
资助金额:$38.79万
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财政年份:1982
-
负责人:ALLAN L DRASH
-
依托单位:
DIABETES CONTROL AND COMPLICATIONS TRIAL
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批准号:3550666
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项目类别:
-
资助金额:$48.32万
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财政年份:1982
-
负责人:ALLAN L DRASH
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依托单位:
DIABETES CONTROL AND COMPLICATIONS TRIAL
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批准号:3550665
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项目类别:
-
资助金额:$36.1万
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财政年份:1982
-
负责人:ALLAN L DRASH
-
依托单位:
DIABETES CONTROL AND COMPLICATIONS TRIAL
-
批准号:3550667
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项目类别:
-
资助金额:$51.71万
-
财政年份:1982
-
负责人:ALLAN L DRASH
-
依托单位:
DIABETES CONTROL AND COMPLICATIONS TRIAL (DCCT)
-
批准号:3550661
-
项目类别:
-
资助金额:$30.96万
-
财政年份:1982
-
负责人:ALLAN L DRASH
-
依托单位:
DIABETES CONTROL AND COMPLICATIONS TRIAL
-
批准号:3550664
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项目类别:
-
资助金额:$36.12万
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财政年份:1982
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负责人:ALLAN L DRASH
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依托单位:
MALFORMATIONS AND FETAL LOSSES IN JUVENILE DIABETES
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批准号:3648394
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项目类别:
-
资助金额:$0.0万
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财政年份:1980
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负责人:ALLAN L DRASH
-
依托单位:
JUVENILE DIABETES MELLITUS EPIDEMIOLOGY AND ETIOLOGY
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批准号:3227245
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项目类别:
-
资助金额:$54.09万
-
财政年份:1978
-
负责人:ALLAN L DRASH
-
依托单位:
JUVENILE DIABETES MELLITUS EPIDEMIOLOGY & ETIOLOGY
-
批准号:3227252
-
项目类别:
-
资助金额:$58.22万
-
财政年份:1978
-
负责人:ALLAN L DRASH
-
依托单位:
JUVENILE DIABETES MELLITUS EPIDEMIOLOGY AND ETIOLOGY
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批准号:3151455
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项目类别:
-
资助金额:$48.52万
-
财政年份:1978
-
负责人:ALLAN L DRASH
-
依托单位:
JUVENILE DIABETES MELLITUS EPIDEMIOLOGY & ETIOLOGY
-
批准号:3227254
-
项目类别:
-
资助金额:$58.32万
-
财政年份:1978
-
负责人:ALLAN L DRASH
-
依托单位:
JUVENILE DIABETES MELLITUS EPIDEMIOLOGY AND ETIOLOGY
-
批准号:3227249
-
项目类别:
-
资助金额:$50.73万
-
财政年份:1978
-
负责人:ALLAN L DRASH
-
依托单位:
JUVENILE DIABETES MELLITUS EPIDEMIOLOGY AND ETIOLOGY
-
批准号:3227251
-
项目类别:
-
资助金额:$58.08万
-
财政年份:1978
-
负责人:ALLAN L DRASH
-
依托单位:
JUVENILE DIABETES MELLITUS EPIDEMIOLOGY AND ETIOLOGY
-
批准号:3227250
-
项目类别:
-
资助金额:$55.36万
-
财政年份:1978
-
负责人:ALLAN L DRASH
-
依托单位:
JUVENILE DIABETES MELLITUS EPIDEMIOLOGY AND ETIOLOGY
-
批准号:3227248
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项目类别:
-
资助金额:$13.58万
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财政年份:1978
-
负责人:ALLAN L DRASH
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依托单位:
JUVENILE DIABETES MELLITUS EPIDEMIOLOGY AND ETIOLOGY
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批准号:2137660
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项目类别:
-
资助金额:$48.91万
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财政年份:1978
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负责人:ALLAN L DRASH
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依托单位:
海外基金