Development of a Herbicide Discovery Platform for commercialisation

该提案的目的是开发一种技术，用于使用申请人实验室开发的新型高通量系统筛选具有选定作用模式的除草剂。该技术建立在对抑制植物生长所需的特定过程的化学物质更敏感的致敏遗传突变植物的产生的基础上。连同已经建立的用于除草剂靶标发现的技术，该技术利用了我们实验室开发的独特特性，遗传系统，所提出的技术将允许申请人开发从化学发现到目标发现的除草剂发现管道。这些技术将通过各种途径为商业活动提供基础。我们通过探路者奖资助的市场研究表明，该平台具有相当大的行业兴趣，并且有潜力产生相当大的收益。收入.

The aim of this proposal is to develop a technology for screening of herbicides with selected modes of action using a novel high throughput system developed in the applicants laboratory.It builds on the generation of sensitised genetic mutant plants that are more sensitive to chemicals that inhibit specific processes required for plant growth.Together with an already established technology for herbicide target discovery that exploits unique characteristics of our genetic system, the proposed technology will allow the applicant to develop of a herbicide discovery pipeline that goes from chemical discovery through to target discovery.Together these technologies will provide the basis of a commercial activity through a variety of routes.Our market research funded through a Pathfinder award indicates that there is considerable interest from industry in the platform and it has the potential to generate considerable revenues.