BEHAVIORAL MEASURES OF BINOCULAR VISION

据估计，大约2%的人患有功能性弱视 普通民众。开发成功的治疗程序 对于功能性弱视必须建立在对 涉及的机制。因此，本提案是对 心理物理学和生理光学，利用一个动物模型 弱视和异常双眼视觉。患有弱视的恒河猴 由刺激剥夺、斜视、慢性睫状肌麻痹和PRIMs引起 解离将被用作对比行为实验的受试者 敏感度、阈值递增敏感度与双眼交互作用 使用分视刺激。视觉诱发电位数据也将 从行为正常的弱视猴子身上收集的。弱视和弱视的数据 非弱视眼睛将根据以下指标进行比较和干预 潜在的生理过程可以用来预测动物的 行为。治疗策略也将被设计出来并在一些 弱视猴子。

It has been estimated that functional amblyopia affects approximately 2% of the general population. The development of successful treatment procedures for functional amblyopia must be based on a thorough understanding of the mechanisms involved. Therefore, the present proposal is an application of psychophysics and physiological optics which utilizes an animal model of amblyopia and anomalous binocular vision. Rhesus monkeys with amblyopia caused by stimulus deprivation, strabismus, chronic cycloplegia and prims dissociation will be used as subjects in behavioral experiments on contrast sensitivity, increment-threshold sensitivity and binocular interactions using dichoptic stimuli. Visual evoked potential data will also be collected on the behaving, amblyopic monkeys. The data of amblyopic and nonamblyopic eyes will be compared and interperted on the basis of underlying physiological process which may be used to predict the animals' behavior. Treatment strategies will also be devised and tested on some of the amblyopic monkeys.