Longitudinal assessment of healthy brain structure and function across the lifespan using 9.4T Magnetic Resonance Imaging

使用磁共振成像对人和动物的大脑进行实时成像，提供了关于大脑在整个生命周期内的结构和功能特性的丰富信息，并确定了与疾病相关的标记。这种专门的成像模式还可以了解不同发育和老龄化人群中的机制和差异。为了使这项研究在世界上处于领先地位，需要最高分辨率的扫描仪提供组织结构和成分的准确细节。我们拥有用于人类和动物大脑成像的出色的集成基础设施，但我们的旧的动物MRI扫描仪需要更换和升级，以便使我们能够看到大脑结构、功能、组成和连接的较小变化，并确保我们的翻译研究保持世界一流水平。

Live Imaging of the human and animal brain, using Magnetic Resonance Imaging, has provided a wealth of information regarding the structural and functional properties of the brain across the lifespan, and identified markers associated with disease. Such specialised imaging modalities can also inform on the mechanisms and variance within populations across development and ageing. For this research to be world leading, the highest resolution scanners are required to provide accurate details of tissue structure and composition. We have an excellent, integrated infrastructure for human and animal brain imaging, but our old, animal MRI scanner needs to be replaced and upgraded, to allow us to see smaller changes in the brain structure, function, composition and connectivity and ensure our translational research remains world class.