MORTALITY BY RACE AMONG LOW BIRTH WEIGHT INFANTS

拟议研究的主要目标是研究 种族与婴儿死亡率之间的关系 婴儿死亡率危险因素的一般模型。有关出生人数的资料 死亡人数将从北部20个县地区获得 卡罗莱纳州(围产期护理第二区)1984-1987年。模型 将包括人口统计特征、医疗和行为特征 母亲和婴儿既往的因素和特征 被发现与低出生体重和婴儿死亡率有关。 专门关注低出生体重儿的分析也 将包括被定义为医学病因学的风险因素 识别直接判断的近端过程和事件 负责早产，并将它们合并到一个 对传统的二分法进行更详细的分类 足月与早产。详细的初步分析将在 在种族和医学病因学之间进行，以及在 他们将其与婴儿死亡率联系在一起。 关于医学病因学的数据将从以下记录中获得 围产期保健区第二医院，数量较少 居民可能去的地区周边的医院 生孩子。这些数据将与计算机化合并 北卡罗来纳州出生/胎儿生命统计信息 死亡和出生/婴儿死亡文件，以及来自 预防早产方案目前正在#年实施。 围产期护理第二区。来自预防的数据 早产计划将提供一组扩展的风险因素 通常不适用于婴儿死亡风险的研究。 作为发展多变量模型的第一步 婴儿死亡率的风险，假设所有风险因素都会影响 婴儿死亡率将被确定为外源性和 插手干预。将在中进一步描述中间变量 它们的类型和与结果的时间接近程度 变量。多变量分析将检验是否合适 单一的婴儿死亡率风险模型，而不是 针对特定女性亚群的单独模特。分析将 对新生儿死亡和新生儿后死亡分别进行。

The primary goal of the proposed study is to examine the relationship between race and infant mortality in the context of a general model of risk factors for infant mortality. Data on births and deaths will be obtained from a 20 county region in North Carolina (Perinatal Care Region Two) for 1984-1987. The model will include demographic characteristics, medical and behavioral factors, and characteristics of the mother and infant previously found to be related to low birth weight and infant mortality. Analyses that focus specifically on low birth weight births also will include a risk factor defined as medical etiology that identifies the proximal processes and events judged directly responsible for a preterm birth, and incorporates them into a more detailed categorization of the traditional dichotomization of term vs. preterm birth. Detailed preliminary analyses will be conducted between race and medical etiology and the manner in which they related to infant mortality. Data on medical etiology will be obtained from records of hospitals in Perinatal Care Region Two, and from a small number of hospitals peripheral to the region where residents may go to give birth. These data will be merged with computerized information from the North Carolina vital statistics birth/fetal death and birth/infant death files, and with data from the prevention of prematurity program currently being conducted in Perinatal Care Region Two. Data from the prevention of prematurity program will provide an expanded set of risk factors generally not available in studies of risk for infant mortality. As the initial step in the development of multivariate models of risk for infant mortality, all risk factors hypothesized to impact on infant mortality will be identified as exogenous and intervening. Intervening variables will be further delineated in terms of their type and temporal proximity to the outcome variable. Multivariate analyses will examine the appropriateness of a single model of risk for infant mortality as opposed to separate models for specific subgroups of women. Analyses will be conducted separately for neonatal and postneonatal deaths.