EFFECTS OF BEHAVIORAL STRESS ON LIPIDS AND LIPOPROTEINS

这个项目评估了慢性行为压力对血脂的影响， 正常血脂健康男性的脂蛋白和载脂蛋白 人口。它测试了几条模型的路径，提出了慢性 行为压力有这样的效果：(A)因为健康状况的改变 行为，如体力活动、体重、饮食和营养 因素；(B)由于压力对血脂的直接影响；和(C)大多数 尤其是在特别敏感的个人子集中。为了测试这一点 模型，这个项目将利用一种慢性职业压力源，急性 实验室挑战、行为评估和饮食挑战。在……里面 此外，它将使用最先进的方法来测量行为 改变，如饮食、体重和体力活动模式。这个 该项目将利用健康的中年男性样本，这些男性已知 可以预见的是，经历了高程度和低程度的慢性职业 压力。受试者每人将参与三种健康行为 评估安排在慢性职业压力较低的时期进行， 紧随其后的是高度慢性职业压力，并以 慢性职业压力低的时期。在这些会议期间， 关于体力活动、饮食摄入量、体重和 还将收集其他几种健康行为。最后一次会议将 最后以实验室课程结束，该课程旨在从心理和 身体上挑战参与者，而血脂、脂蛋白和 载脂蛋白正在进行评估。统计分析是 假设驱动的，旨在专门测试几条路径的 建议的模型。

This project assesses the effects of chronic behavioral stress on lipids, lipoproteins, and apolipoproteins in a healthy male, normolipidemic population. It tests several pathways of model proposing that chronic behavioral stress has this effect (a) because of alterations in health behaviors, such as physical activity, body weight, diet and nutritional factors; (b) because of direct effects of stress on lipids; and (c) most notably in a particularly sensitive subset of individuals. To test this model, this project will utilize a chronic occupational stressor, acute laboratory challenges, behavioral assessment, and a dietary challenge. In addition, it will employ state-of-the-art methods of measuring behavioral changes, such as diet, body weight, and physical activity patterns. The project will utilize a sample of health middle-aged males who are known to predictably experience both high and low degrees chronic occupational stress. Subjects will each participate in three health behavior assessments, scheduled during a period of low chronic occupational stress, followed by one of high chronic occupational stress, and concluding With a period of low chronic occupation stress. During these sessions, information regarding physical activity, dietary intake, body weight and several other health behaviors will be collected. The final session will conclude with a laboratory session designed to psychologically and physically challenge the participants, while lipids, lipoproteins, and apolipoproteins are being assessed. Statistical analyses are hypothesis-driven and designed to specifically test several pathways of the proposed model.