THE EPIDEMIOLOGY OF PERSISTENT CHILD PSYCHOPATHOLOGY

本提案中所述的流行病学研究是基于近 对1000名随机抽样的1至10岁儿童的母亲进行了采访。 数据 收集了儿童的情绪和行为方面的资料， 问题和能力，儿童的健康史，儿童抚养和 其他家庭结构和环境变量的原始波 1975年数据采集。 心理测量学和实质性的研究，这些 数据将在本赠款期内完成。 对母亲和儿童进行了后续访谈 在孩子们9到18岁的时候 重新采访包括DSM III 基于诊断访谈，从原始访谈中得出的量表， 以及关于家庭和家庭外环境的广泛数据。 此外，本发明还提供了一种方法， 对100个家庭进行重新采访，以提供临床验证， 为评估和改进 诊断面试 目前建议的具体目标包括心理测量 调查诊断中的方法学问题。 改善 基于这些分析的诊断仪器将应用于 新一轮的数据收集，母亲和孩子将再次 使用旨在涵盖相同问题的结构化工具进行访谈 在当前的浪潮中。 此外，重新采访了一个样本， 年龄在15到20岁之间的大一点的孩子将和成年人一起被带走 DIS. 该子研究将能够将诊断翻译为 该样品与其他可用样品的比较。 这些数据将用于确定以下疾病的患病率和持续性： 儿童精神障碍及其前因问题 童年早期 在所有三个时间点收集的数据将 用于确定精神病理学的危险因素和伴随因素。 在 此外，研究将评估这些风险因素的普遍性， 他们对生活在不同家庭外的儿童的相对效力 环境. 数据分析将包括复制以前的 研究结果表明，不同的环境影响，并测试 理论和经验以及衍生模型。

The epidemiological study described in this proposal is based on nearly 1000 interviews of mothers of randomly sampled children ages 1 to 10. Data were collected with regard to the children's emotional and behavioral problems and competencies, children's health histories, child rearing and other family structure and environmental variables in the original wave of data collection during 1975. Psychometric and substantive studies of these data will have been completed during the current grant period. Follow up interviews of both mothers and children have been carried out when the children were ages 9 to 18. The reinterviews included DSM III based diagnostic interviews, scales derived from the original interviews, and extensive data on familial and extrafamilial environment. In addition, a reinterview of 100 families to provide a clinical validation will have been completed to provide the basis for assessment and improvement of the lay diagnostic interviews. The specific aims for the current proposal include psychometric investigations into methodological issues in diagnosis. Improvements in the diagnostic instrument based on these analyses will then be applied in a new wave of data collection in which mothers and children will again be interviewed with a structured instrument designed to cover the same issues addressed in the current wave. In addition, a reinterview of a sample of the older children, now ages 15 to 20, will be carried out with the adult DIS. This substudy will enable a translation of diagnosis across instruments and comparison of this sample with other available samples. The data will be employed to determine the prevalence and persistance of psychiatric disorders in children and their antecedents in the problems of early childhood. Data collected at all three points in time will be employed to determine risk factors and concomitants of psychopathology. In addition, the study will assess the generality of these risk factors and their relative potencies for children living in different extra-familial environments. The data analysis will include replication of previous findings suggesting differential environmental effects, and testing of theoretically and empirically and derived models.