Nano-agents for read / write microscopy and nano-macro bridging

纳米尺度对我们的世界是极其重要的，例如：-在这个尺度上，我们在宏观尺度上使用的材料的许多特性都是确定的-许多生物系统具有纳米尺度的结构，并通过在纳米尺度上发生的一系列反应来运作。纳米尺度上的交流对我们了解更广阔的世界越来越重要，然而，比在更大尺度上做到这一点要困难得多。有很多工具可以在小尺度上探测事物，但它们有很多缺点，例如，光学显微镜没有足够的分辨率来观察纳米尺度的事物；原子力显微镜通常用于纳米级物体成像，但它无法看到细胞等物体的内部；电子显微镜被广泛用于纳米尺度的物体成像和书写，但它不能用于大型或有生命的物体。该提案旨在开发一种与纳米尺度通信的新方法，通过使用小型设备“纳米代理”，可以在纳米尺度环境中获取信息。它们可以远程操作，无需与仪器接触，因此它们可以放置在物体内部，甚至是大型和有生命的物体。它们将使纳米级环境能够被感知，并提供一种改变纳米级环境的方法。这将开辟探索和与纳米尺度相互作用的新途径。

The nanoscale is extremely important to our world, for instance:- At this scale many of properties of materials we use at the macroscale are determined- Many biological systems have structure at the nanoscale and operate through series of reactions that take place on the nanoscaleCommunicating with the nanoscale is increasingly important for our understanding of our wider world, however, it is much more difficult to do this than at larger scales. There are lots of tools for probing things at the small scale but these have many drawbacks, for instance, optical microscopy does not have sufficient resolution to see things at the nanoscale; atomic force microscopy, which is often used to image object at the nanoscale, can't see inside things like cells; and electron microscopy which is widely used to image and write objects at the nanoscale can't be used on large or living objects.This proposal aims to develop a new method of communicating with the nanoscale by using small devices, "nano-agents", which can get information in and out of the nanoscale environment. These will operate remotely and without contact with the instrument so they can be placed inside objects, even large and living ones. They will enable the nanoscale environment to be sensed and provide a way to change the nanoscale environment. This will open up new ways to explore and interact with the nanoscale.