CHANGE IN CHD RISK FACTORS IN YOUNG ADULTS

冠状动脉危险因素的流行病学研究已经进行 主要是中年人、儿童和 adolscents. 对男性的这些危险因素知之甚少 和20-29岁的妇女。 这项研究将前瞻性地检查 295名青年人血脂、脂蛋白和血压的变化 在比弗县被跟踪了16年的成年人 study. 进行了三项横断面检查：1） 1972-1973年; 2）1980-1981年; 3）1988-1989年。 我们会研究 总胆固醇变化的预测因素（从检查1到 检查3，以及LDL-C、HDL-C和甘油三酯在 检查2和3。我们还将研究几个方面的稳定性 健康习惯和行为，如吸烟，饮酒， 坚持低脂肪/低胆固醇饮食和体力活动。 体重增加和口服避孕药的使用已经显示在以前的 分析是几种脂质和脂蛋白的强预测因子。 这项研究应该提供重要的见解的决定因素， 年轻人的冠心病危险因素，并可能支持这些论点 他们倾向于早期识别和干预年轻人， 冠心病候选人

Epidemiologic studies of coronary risk factors have been performed primarily in populations of middle-aged adults, children, and adolscents. Relatively little is known about these risk factors in men and women 20-29 years of age. This study will prospectively examine changes in lipids, lipoproteins, and blood pressure among 295 young adults who have been followed for sixteen years in the Beaver County study. Three cross-sectional examinations have been carried out: 1) 1972-1973; 2) 1980-1981; and 3) 1988-1989. We will examine the predictors of change in total cholesterol (from examination 1 to examination 3, and change in LDL-C, HDL-C, and triglycerides between examinations 2 and 3. We will also investigate the stability in several health habits and behaviors such as cigarette smoking, alcohol use, adherence to a low fat/low cholesterol diet, and physical activity. Weight gain and oral contraceptive use have been shown in previous analyses to be strong predictors of several lipids and lipoproteins. This study should provide important insights into the determinants of CHD risk factors in young adults and may bolster the argument of those who favor the early identification of and intervention in the young coronary candidate.