PREVALENCE OF G-6-PD DEFICIENCY IN GLAUCOMA PATIENTS

原发性开角型青光眼生化病因的一种学说 (POAG)是指房水流出时对组织的氧化损伤 系统会导致流出设备的减少。在一项初步研究中， 我们发现了7例葡萄糖-6-磷酸脱氢酶(G-6-PD)缺乏症 30名黑人男性POAG患者(23%)，是我们预期的两倍 黑人男性人口。 180名黑人男性POAG患者(例)和180名 来自其他诊所(对照)的黑人男性患者将接受筛查 G-6-PD缺乏症判断此酶缺乏症是否较多 常见于开角型青光眼患者。

One theory of the biochemical etiology of primary open angle glaucoma (POAG) is that oxidative damage to the tissues of the aqueous outflow system causes a reduction in facility of outflow. In a preliminary study, we have found glucose-6-phosphate dehydrogenase (G-6-PD) deficiency in 7 of 30 black male POAG patients (23%), twice the rate we would expect in the black male population. One hundred eighty (180) black male patients with POAG (cases) and 180 black male patients from other clinics (controls) will be screened for G-6-PD deficiency to determine whether this enzyme deficiency is more common in POAG patients.