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NEUROLOGICAL AND NEUROPSYCHOLOGICAL ASPECTS OF HIV

NEUROLOGICAL AND NEUROPSYCHOLOGICAL ASPECTS OF HIV
HIV 的神经学和神经心理学方面
批准号:
3436158
负责人:
ROBERT M LEVY
金额:
$3.0万
依托单位国家:
美国
项目类别:
财政年份:
1990
资助国家:
美国
项目状态:
已结题
起止时间:
1990-04-01 至 1991-03-31

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中文摘要
翻译
感染人类免疫缺陷病毒(HIV-1)不仅会导致 免疫功能障碍不仅表现在神经学和神经心理学上 生病了。10%的获得性免疫缺陷患者 综合征(艾滋病)以神经系统症状为首发症状 疾病,37%的艾滋病患者有明显的神经功能障碍 在他们一生中,75%的人有神经病理异常 验尸报告。据报道,有8%到67%的人有神经心理异常 在艾滋病患者和10%至40%的HIV-1感染者中。 神经系统疾病不仅仅是机会主义过程的结果 但也是神经系统感染HIV-1原发的结果。 因此,大量感染艾滋病毒-1的人也面临着 患有神经或神经心理疾病,即使在不在的情况下也是如此 免疫功能障碍或全身疾病。 自从1983年首次报道与HIV-1相关的神经系统疾病以来, 艾滋病神经和神经心理并发症的研究进展 HIV-1感染为我们提供了一些新的见解 人类免疫缺陷病毒1型神经系统感染机制及临床表现 系统。人类免疫缺陷病毒的神经学和神经心理学目标 感染,年度国际会议之前的年度卫星会议 关于艾滋病的会议,是将世界各地的专家汇聚一堂 HIV感染的几个方面及其神经学和神经心理学 并发症。本次会议将以几次全体会谈开始, 将回顾这些领域最重要的最新研究成果。 在接下来的公开科学会议上,来自 世界各地将能够分享他们的研究成果 并为这一领域的研究提供了一个论坛进行讨论。vt.在.上 每两年举行一次,为期三天的会议的第一天将包括 神经学和神经心理学并发症概述课程 艾滋病和艾滋病毒感染,由这些领域的世界专家介绍。 这次国际科学会议应该会带来更多 对艾滋病的神经学和神经心理学方面的认识 艾滋病毒感染;这一认识的提高应导致改善对 HIV感染者以及指导和协调未来 对这一关键领域进行研究。我们在魁北克市的第一次年会, 在蒙特利尔举行的关于艾滋病的第Vth国际会议之前, 来自世界各地的220多名参与者取得了绝对的成功。使用 这一压倒性的初步反应,我们计划继续神经学 和神经心理学方面
英文摘要
Infection with the human immunodeficiency virus (HIV-1) results not only in immunologic dysfunction but also in neurological and neuropsychological illness. Ten percent of all patients with the acquired immunodeficiency syndrome (AIDS) have a neurological complaint as their first sign of illness, 37% of AIDS patients have significant neurological dysfunction during their lifetime and 75% have neuropathological abnormalities on autopsy. Neuropsychological abnormalities have been reported in 8% to 67% of patients with AIDS and in 10% to 40% of people with HIV-1 infection. Neurological illness arises not only as a result of opportunistic processes but also as a result of primary HIV-1 infection of the nervous system. Thus, the large numbers of people infected with HIV-1 are also at risk of developing neurological or neuropsychological illness, even in the absence of immunological dysfunction or systemic illness. Since the first reports of HIV-1-related neurological illness in 1983, research into the neurological and neuropsychological complications of AIDS and HIV-1 infection has provided a number of new insights into the mechanisms and clinical manifestations of HIV-1 infection of the nervous system. The goal of Neurological and Neuropsychological Aspects of HIV Infection, an annual satellite meeting prior to the annual International Conference on AIDS, is to bring together the world's experts in various aspects of HIV infection and its neurological and neuropsychological complications. This meeting will begin with several plenary talks which will review the most important recent results of research in these areas. During the open scientific sessions which will follow, researchers from around the world will be able to share the results of their research in this field and have a forum for the discussion of this research. On a biyearly basis, the first day of this three day meeting will consist of an overview course on the neurological and neuropsychological complications of AIDS and HIV infection, presented by the world's experts in these areas. This international scientific meeting should result in an increased awareness of the neurological and neuropsychological aspects of AIDS and HIV infection; this increased awareness should result in improved care of patients with HIV infection as well as directing and coordinating future research into this critical area. Our first annual meeting in Quebec City, prior to the Vth International Conference on AIDS in Montreal, was an unqualified success with over 220 participants from around the world. With this overwhelming initial response, we plan to continue the Neurological and Neuropsychological Aspects
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