1991 TESTIS WORKSHOP

北美睾丸研讨会已经举办了近二十年。 到今年为止，这个研讨会一直由美国国立卫生研究院的合同资助。 每个研讨会都侧重于睾丸功能的各个方面。 这些讲习班一直是信息交流的重点 睾丸功能已经有二十年了，而且大多数人都认为 与会者是他们所在领域的主要会议。 最近，我们对这一问题的理解出现了迅速而戏剧性的发展 潜在的基因组表达和控制发生在 精子发生、精子成熟和受精是该项目的领头羊 委员会将1991年讲习班的重点放在男性生殖器的某些方面 细胞在发育过程中通过复合体形成精原细胞 精子发生和精子成熟到受精的阶段。 我们对类固醇激素如何作用的理解最近取得了突破 通过它们的受体和类固醇激素之间令人着迷的相似性 首先将介绍受体。这之后将是基因 精子发生的控制和构成精子的基因组决定 男的是男的。荷尔蒙环境的复杂微调使 然后将介绍将发生的精子发生。令人兴奋 在我们对结构和结构的理解上有了新的发展 精子特有细胞器的功能及特异基因 在精子发生过程中的表达。生殖细胞如何与它们的 精子发生过程中的环境(生殖细胞-支持细胞相互作用)和 之后将讨论附睾期的情况。最后，应用程序 在我们对精子运动和精子运动的理解上的技术突破 将介绍精子-卵子相互作用的基本过程。 所有演讲的形式将是25分钟的演讲，然后是 对每篇论文进行20分钟的深入讨论。漫长的咖啡和午餐 休息时间将有助于促进与会者之间的进一步交流。 将与葡萄酒和奶酪一起进行的两个海报会议 课程将允许所有参与者提交自愿捐款 他们最新的研究成果。

The North American Testis Workshop has been held for nearly twenty years. This Workshop has, until this year, been funded by contracts from NIH. Each of the Workshops has focused on various facets of testicular function. These Workshops have served as the focus for information exchange on testicular function for two decades and have been perceived by most of the participants as the major meeting in their field. Recent rapid and dramatic developments in our understanding of the underlying genomic expression and control that takes place during spermatogenesis and sperm maturation and fertilization have led the Program Committee to focus the 1991 Workshop on selective aspects of the male germ cell as it progresses form being a spermatogonium through the complex phases of spermatogenesis and sperm maturation to fertilization. The recent breakthroughs in our understanding of how steroid hormones act via their receptors and the fascinating similarity amongst steroid hormone receptors will first be presented. This will be followed by the genetic control of spermatogenesis and the genomic determination of what makes a male a male. The complex fine tuning of the hormonal milieu that allows spermatogenesis to take place will then be presented. Exciting developments have occurred in our understanding of the structure and function of organelles specific to spermatozoa as well as specific gene expression during spermatogenesis. How germ cells relate to their environment during spermatogenesis (germ-Sertoli cell interactions) and during epididymal transit will then be discussed. Finally, the application of the technical breakthroughs in our understanding of sperm motility and of the underlying processes of sperm-egg interaction will be presented. The format of all presentations will be a 25 minute talk followed by a thorough 20 minute discussion of each paper. The long coffee and lunch breaks will help promote further communication amongst the participants. Two poster sessions that will be given in conjunction with wine and cheese sessions will allow all participants to present voluntary contributions of their most recent research findings.