EPSRC and BBSRC Centre for Doctoral Training in Synthetic Biology

合成生物学CDT （SBCDT）将专注于基于生物的部件，新设备和系统的设计和工程，以及从分子到生物体的所有尺度的现有自然生物系统的重新设计。它的显著特点将是广度和深度：SBCDT将建立在牛津大学、布里斯托尔大学和华威大学的研究环境所提供的多学科专业知识的基础上，提供涵盖这一极其广泛的范围的所有部分的培训，不仅包括单个细胞，还包括自组装的仿生系统、工程微生物群体和多细胞生物，结合工程、生命和物理科学的多个视角。我们认为，这样的覆盖面是至关重要的合成生物学的新兴领域；但是，同样地，这只有通过像我们这样的机构之间的合作才能实现。在与我们的工业和其他合作伙伴的密切合作下，我们将解决最近发布的合成生物学路线图的建议，该路线图旨在建立一个“熟练，充满活力和资金充足的英国合成生物学社区”，该社区“有机会彻底改变英国生物能源和生物技术的主要行业”（大学和科学部长David Willetts）。SBCDT将提供5个每年15名学生的强大队列，提供高质量和高度实用的合成生物学培训，以填补这一技能空白，并培养下一代国际优秀的研究人员和行业领导者。培训将以多样化和创新的项目为基础，从课堂和研讨会到学生主导的小组项目，以及在合成生物学发展前沿的探索性和博士研究项目。伦理、法律和社会方面的考虑、公众参与以及工业、学术和合成生物学潜在最终用户的需求将从一开始就纳入培训计划。我们将在这个群体中产生一种复杂的、多方面的对合成生物学的机会和潜在危险的认识，这对负责任的创新至关重要。培训将由世界领先的研究人员团队提供，与学生入学一样，他们将是高度多学科的。我们会确保大学科学研究小组充分利用三所大学提供的机会，并在一群有凝聚力的学生的共同影响下，推动大学间的研究活动。这将确保整个英国合成生物学的发展，并加强英国在这个非常有前途的领域的全球竞争力。

The Synthetic Biology CDT (SBCDT) will focus on the design and engineering of biologically based parts, novel devices and systems as well as the re-design of existing, natural biological systems across all scales from molecules to organisms. Its distinguishing feature will be breadth and depth: the SBCDT will build on the multi-disciplinary expertise offered by the research environment at the Universities of Oxford, Bristol and Warwick to provide training that covers all parts of this extremely broad remit, including not only individual cells but self-assembled biomimetic systems, engineered microbial communities and multicellular organisms, combining the multiple perspectives of engineering and the life and physical sciences. We believe that such coverage is vital in the emerging area of Synthetic Biology; but, equally, this is only currently possible through a collaborative effort across institutions such as ours. In close partnership with our industrial and other partners, with whom we have developed this bid, we will address the recommendation of the recently published Synthetic Biology Roadmap for a "skilled, energized and well-funded UK-wide Synthetic Biology community", which has "the opportunity to revolutionise major industries in bio-energy and bio-technology in the UK" (David Willetts, Minister for Universities and Science). The SBCDT will provide five annual 15-student strong cohorts with high-quality and highly practical training in Synthetic Biology that will fill this skills gap and deliver the next generation of internationally excellent researchers and industrial leaders. The training will be based on a varied and innovative programme that will range from classes and seminars to student-led group projects and exploratory and PhD research projects at the forefront of the development of Synthetic Biology. Ethical, Legal and Social considerations, public engagement, and the needs of industrial, academic and potential end users of Synthetic Biology will be integrated into the training programme from the start. We will engender within the cohort a sophisticated, multi-faceted appreciation of the opportunities and potential hazards of Synthetic Biology that is essential to Responsible Innovation. Training will be delivered by a team of world-leading researchers which, like the student intake, will be highly multidisciplinary. We will ensure that the SBCDT takes full advantage of the opportunities provided by the three Universities and will act as a catalyst for inter-university research initiatives underpinned by the unifying influence of a cohesive cohort of students. This will ensure development of Synthetic Biology across the UK and that the UK strengthens its global competitiveness in this very promising field.